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- Publications
- Influence
IL-31: a new link between T cells and pruritus in atopic skin inflammation.
- Eniko Sonkoly, A. Muller, +12 authors B. Homey
- Medicine
- The Journal of allergy and clinical immunology
- 1 February 2006
BACKGROUND
IL-31 is a novel T-cell-derived cytokine that induces severe pruritus and dermatitis in transgenic mice, and signals through a heterodimeric receptor composed of IL-31 receptor A and… Expand
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons
- J. Gregorio, S. Meller, +7 authors M. Gilliet
- Biology, Medicine
- The Journal of experimental medicine
- 20 December 2010
Cutaneous injury in mice drives transient TLR7- and TLR9-mediated production of type I interferon by plasmacytoid dendritic cells, which is required for re-epithelialization of the skin.
CCL1-CCR8 Interactions: An Axis Mediating the Recruitment of T Cells and Langerhans-Type Dendritic Cells to Sites of Atopic Skin Inflammation1
- M. Gombert, M. Dieu-Nosjean, +21 authors B. Homey
- Biology, Medicine
- The Journal of Immunology
- 15 April 2005
Atopic dermatitis represents a chronically relapsing skin disease with a steadily increasing prevalence of 10–20% in children. Skin-infiltrating T cells, dendritic cells (DC), and mast cells are… Expand
CC Chemokine Ligand 18, An Atopic Dermatitis-Associated and Dendritic Cell-Derived Chemokine, Is Regulated by Staphylococcal Products and Allergen Exposure1
- A. Pivarcsi, M. Gombert, +14 authors B. Homey
- Medicine, Biology
- The Journal of Immunology
- 1 November 2004
Atopic dermatitis is a chronic inflammatory skin disease with a steadily increasing prevalence. Exposure to allergens or bacterial superantigens triggers T and dendritic cell (DC) recruitment and… Expand
Tacrolimus ointment does not affect collagen synthesis: results of a single-center randomized trial.
- S. Reitamo, J. Rissanen, +5 authors A. Lauerma
- Medicine
- The Journal of investigative dermatology
- 1 September 1998
We conducted a randomized, double-blind, placebo-controlled trial to assess the atrophogenicity of tacrolimus ointment. In a combined group of atopic dermatitis patients (n = 14) and healthy… Expand
A multicenter study of patch test reactions with dental screening series.
- L. Kanerva, T. Rantanen, +13 authors A. Vuorela
- Chemistry, Medicine
- American journal of contact dermatitis : official…
- 1 June 2001
BACKGROUND
Dental products contain many allergens, and may cause problems both for patients undergoing dental treatment and for dental personnel because of occupational exposure. Individual patch… Expand
Topical Superantigen Exposure Induces Epidermal Accumulation of CD8+ T Cells, a Mixed Th1/Th2-Type Dermatitis and Vigorous Production of IgE Antibodies in the Murine Model of Atopic Dermatitis1
- T. Savinko, A. Lauerma, +8 authors H. Alenius
- Medicine
- The Journal of Immunology
- 15 December 2005
Patients with atopic dermatitis (AD) have repeated cutaneous exposure to both environmental allergens and superantigen-producing strains of Staphylococcus aureus. We used a murine model of AD to… Expand
The chemokine receptor CCR3 participates in tissue remodeling during atopic skin inflammation.
- K. Gáspár, G. Kukova, +15 authors B. Homey
- Biology, Medicine
- Journal of dermatological science
- 1 July 2013
BACKGROUND
Recent studies provided insights into the recruitment and activation pathways of leukocytes in atopic dermatitis, however, the underlying mechanisms of tissue remodeling in atopic skin… Expand
Absorption of topical tacrolimus (FK506) in vitro through human skin: comparison with cyclosporin A.
- A. Lauerma, C. Surber, H. Maibach
- Chemistry, Medicine
- Skin pharmacology : the official journal of the…
- 1997
Cyclosporin A (CsA) is efficacious in many dermatoses as an oral but not as a topical form, while tacrolimus (FK506) has been shown to be effective in both forms. As inadequate skin absorption has… Expand
Repeated epicutaneous exposures to ovalbumin progressively induce atopic dermatitis‐like skin lesions in mice
- G. Wang, T. Savinko, +5 authors H. Alenius
- Medicine
- Clinical and experimental allergy : journal of…
- 1 January 2007
Background Atopic dermatitis (AD) is a chronic skin disease in which environmental factors play a great role. A widely used murine model for AD has provided a useful tool to study the disease.