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Monobactams

Known as: beta Lactams, Monocyclic, beta lactam antibiotic, Monocyclic beta-Lactams 
A compound with a four member amide ring (beta-lactam), where one member is the amide nitrogen and another is the carbonyl carbon, with bactericidal… 
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (18)

Amoxicillin / ClavulanateAztreonamBAL 30072BAL29880

Broader (2)

AntibioticsLactams
Aztreonam 2000 MG InjectionIn Bloodagonistsantagonists & inhibitors

Papers overview

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Highly Cited
1983
Highly Cited
1983
Penicillin-binding Proteins and the Future of P-Lactam Antibiotics
Highly Cited
1982
Highly Cited
1982
Resistance to cefamandole: a collaborative study of emerging clinical problems.
Cefamandole resistance in five patients was studied. Microorganisms emerged resistant to cefamandole during therapy with the drug… 
Highly Cited
1980
Highly Cited
1980
Intrinsic resistance to beta-lactam antibiotics in Staphylococcus aureus.
1979
1979
PS-5, a new beta-lactam antibiotic. I. Taxonomy of the producing organism, isolation and physico-chemical properties.
Antibiotic PS-5 is a new beta-lactam antibiotic isolated from fermentation broths of Streptomyces sp. strain A271. The strain was… 
1979
1979
Comparison of antibiotic regimens for treatment of experimental pneumonia due to Pseudomonas.
The high mortality associated with pneumonia due to Pseudomonas aeruginosa prompted a comparative trial of several currently… 
Review
1977
Review
1977
Biosynthesis of polyene macrolide antibiotics.
BIOSYNTHESIS OF THE MACROLIDE RING .. Precursors of the Macrolide Ring .. Polyketide Synthesis and Fatty Acid Synthesis .. Acyl… 
Highly Cited
1977
Highly Cited
1977
Nuclear analogues of beta-lactam antibiotics. I. the total synthesis of a 7-oxo-1,3-diazabicyclo[3.2.0]heptane-2-carboxylic acid via a versatile monocyclic beta-lactam intermediate.
Highly Cited
1976
Highly Cited
1976
Conformational analysis by nuclear magnetic resonance. Nitrogen-15 and carbon-13 spectra of lactams.
The 5-, 6-, 7-, 8-, 9-, and 13-numbered lactams have been studied as simple models for the amide linkage. ^(15)N and ^(13)C… 
Highly Cited
1976
Highly Cited
1976
β-Lactum antibiotics alone or in combination with gentamicin for therapy of gram-negative bacillary infections in neutropenic patients
Abstract:This study was initiated to determine whether antibiotic combinations are superior to single antibiotics for the… 
Highly Cited
1974
Highly Cited
1974
Letter: Total synthesis of beta-lactam antibiotics. VII. Total synthesis of (plus or minus)-1-oxacephalothin.