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Monobactams

Known as: beta Lactams, Monocyclic, beta lactam antibiotic, Monocyclic beta-Lactams 
A compound with a four member amide ring (beta-lactam), where one member is the amide nitrogen and another is the carbonyl carbon, with bactericidal… 
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (18)

Amoxicillin / ClavulanateAztreonamBAL 30072BAL29880

Broader (2)

AntibioticsLactams
Aztreonam 2000 MG InjectionIn Bloodagonistsantagonists & inhibitors

Papers overview

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Highly Cited
1986
Highly Cited
1986
Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations.
A series of inhibitors of angiotensin converting enzyme (ACE, dipeptidyl carboxypeptidase, EC 3.4.15.1) is described which… 
Highly Cited
1983
Highly Cited
1983
Penicillin-binding Proteins and the Future of P-Lactam Antibiotics
Highly Cited
1982
Highly Cited
1982
Resistance to cefamandole: a collaborative study of emerging clinical problems.
Cefamandole resistance in five patients was studied. Microorganisms emerged resistant to cefamandole during therapy with the drug… 
Highly Cited
1981
Highly Cited
1981
In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistance
N-Formimidoyl thienamycin (N-F-thienamycin) and moxalactam were compared with other currently available and investigational… 
Highly Cited
1979
Highly Cited
1979
LY-127935: a novel beta-lactam antibiotic with unusual antibacterial activity
The in vitro activity of LY-127935, a new beta-lactam antibiotic, was examined by using 370 clinical bacterial strains. In… 
Highly Cited
1979
Highly Cited
1979
In Vitro Activity of LY127935
LY127935 is a unique new β-lactam antibiotic. Its activity against 536 clinical isolates was studied by using microdilution… 
Review
1977
Review
1977
Biosynthesis of polyene macrolide antibiotics.
BIOSYNTHESIS OF THE MACROLIDE RING .. Precursors of the Macrolide Ring .. Polyketide Synthesis and Fatty Acid Synthesis .. Acyl… 
Highly Cited
1977
Highly Cited
1977
Nuclear analogues of beta-lactam antibiotics. I. the total synthesis of a 7-oxo-1,3-diazabicyclo[3.2.0]heptane-2-carboxylic acid via a versatile monocyclic beta-lactam intermediate.
Highly Cited
1976
Highly Cited
1976
Conformational analysis by nuclear magnetic resonance. Nitrogen-15 and carbon-13 spectra of lactams.
The 5-, 6-, 7-, 8-, 9-, and 13-numbered lactams have been studied as simple models for the amide linkage. ^(15)N and ^(13)C… 
Highly Cited
1974
Highly Cited
1974
Letter: Total synthesis of beta-lactam antibiotics. VII. Total synthesis of (plus or minus)-1-oxacephalothin.