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ABSTRACT The outer membrane of Gram-negative bacteria presents an efficient barrier to the permeation of antimicrobial molecules… Expand OBJECTIVES
We investigated the activity of BAL30072, a dihydroxypyridone monosulfactam, against carbapenem-resistant… Expand OBJECTIVES
Carbapenem resistance in Gram-negative bacteria, mediated by restricted net influx and carbapenem-hydrolysing… Expand ABSTRACT BAL30072 is a monosulfactam conjugated with an iron-chelating dihydroxypyridone moiety. It is active against Gram… Expand New antibiotic agents are desperately needed to treat the multidrug-resistant pathogens that continue to emerge at alarming rates… Expand OBJECTIVES
The activity of BAL30072 was compared with that of anti-Acinetobacter reference drugs against meropenem-non… Expand OBJECTIVES
New antibiotics that are active against multidrug-resistant (MDR) Acinetobacter baumannii are urgently needed… Expand Burkholderia pseudomallei is an intrinsically antibiotic-resistant Category B priority pathogen and the aetiological agent of… Expand ABSTRACT BAL30072 is a new monocyclic β-lactam antibiotic belonging to the sulfactams. Its spectrum of activity against… Expand BACKGROUND
We tested the activity of BAL30072, a novel siderophore monobactam, against multiresistant clinical isolates of… Expand