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The increasing number of individuals with comorbidities poses an urgent need to improve the management of patients with multiple… Expand The sulfonylurea receptor 1 (Sur1)–transient receptor potential 4 (Trpm4) channel is an important molecular element in focal… Expand Addictive diseases, including addiction to heroin, prescription opioids, or cocaine, pose massive personal and public health… Expand Unravelling the pathophysiology of depression is a unique challenge. Not only are depressive syndromes heterogeneous and their… Expand Depression is a condition with a complex biologic pattern in etiology. Environmental stressors modulate subsequent vulnerability… Expand Zebrafish provide a rapid and effective means for assessing gene function in the vertebrate nervous system. By employing gain… Expand The nicotinic acetylcholine receptor is the prototype ligand-gated ion channel. A number of aromatic amino acids have been… Expand Publisher Summary This chapter discusses the molecular neurobiology of the GABAA receptor. The GABAA receptor is responsible for… Expand Recent developments in DNA and oligonucleotide chemistry have made it possible to modify nucleotides and link quite complex… Expand The acetylcholine receptor (AChR) is the most thoroughly characterized component ofthe neuromuscular transduction process… Expand