FAQ

Mitotic Anaphase

Known as: Anaphase 
The third phase of mitosis during which the two groups of daughter chromosomes separate and move along the fibers of the central spindle, each toward… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1942-2017
05010015019422016

Related topics

Related topics

10 relations
AURKA geneAURKA wt AlleleAurora Kinase ACell Proliferation
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Broader (2)

AnaphaseM Phase, Mitotic

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Mitotic Anaphase
Cell Proliferation
Mitogens
Mitotic Cell Cycle
Intercellular Communication Process
Chromosome Segregation

Papers overview

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Highly Cited
2007
Highly Cited
2007
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
The spindle checkpoint prevents chromosome mis-segregation by delaying sister chromatid separation until all chromosomes have… (More)
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Highly Cited
2004
Highly Cited
2004
Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells
We have found that key mitotic regulators show distinct patterns of degradation during exit from mitosis in human cells. Using a… (More)
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Highly Cited
2003
Highly Cited
2003
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… (More)
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Highly Cited
2003
Highly Cited
2003
Mitotic regulation of the human anaphase-promoting complex by phosphorylation.
The anaphase-promoting complex (APC) or cyclosome is a ubiquitin ligase that initiates anaphase and mitotic exit. APC activation… (More)
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Highly Cited
2002
Highly Cited
2002
Separase, Polo Kinase, the Kinetochore Protein Slk19, and Spo12 Function in a Network that Controls Cdc14 Localization during Early Anaphase
In budding yeast, the phosphatase Cdc14, a key regulator of exit from mitosis, is released from its inhibitor Cfi1/Net1 in the… (More)
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Highly Cited
2001
Highly Cited
2001
Emi1 Is a Mitotic Regulator that Interacts with Cdc20 and Inhibits the Anaphase Promoting Complex
We have discovered an early mitotic inhibitor, Emi1, which regulates mitosis by inhibiting the anaphase promoting complex… (More)
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Highly Cited
1998
Highly Cited
1998
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.
The spindle assembly checkpoint mechanism delays anaphase initiation until all chromosomes are aligned at the metaphase plate… (More)
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Highly Cited
1996
Highly Cited
1996
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p.
Anaphase initiation has been postulated to be controlled through the ubiquitin-dependent proteolysis of an unknown inhibitor… (More)
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Highly Cited
1994
Highly Cited
1994
Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle
To test the popular but unproven assumption that the metaphase-anaphase transition in vertebrate somatic cells is subject to a… (More)
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Highly Cited
1991
Highly Cited
1991
Cyclin is degraded by the ubiquitin pathway
Cyclin degradation is the key step governing exit from mitosis and progress into the next cell cycle. When a region in the N… (More)
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