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Mitogen-Activated Protein Kinase 11

Known as: p38(beta) MAP Kinase, p38beta MAP Kinase, SAP Kinase-2 
A 38-kDa mitogen-activated protein kinase that is expressed in a broad variety of cell types. It may play a role in regulating cell proliferation and… Expand
National Institutes of Health

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In BloodMAP kinase activityMAPK11 geneMAPK11 wt Allele
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MAPK11 protein, human

Papers overview

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Highly Cited
2016
Highly Cited
2016
Feedback Regulation of ABA Signaling and Biosynthesis by a bZIP Transcription Factor Targets Drought-Resistance-Related Genes1[OPEN]
Abscisic acid signaling and biosynthesis are feedback-regulated by transcription factor OsbZIP23 that targets diverse genes… Expand
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2003
2003
Role of 14-3-3-mediated p38 mitogen-activated protein kinase inhibition in cardiac myocyte survival.
14-3-3 family members are dimeric phosphoserine-binding proteins that regulate signal transduction, apoptotic, and checkpoint… Expand
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2002
2002
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells.
Tau is a microtubule-associated protein that is abnormally hyperphosphorylated in the filamentous lesions that define a number of… Expand
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Highly Cited
2001
Highly Cited
2001
Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells.
Apoptosis induction may be a mechanism mediating the anticancer activity of selenium. Our earlier work indicated that distinct… Expand
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Highly Cited
2000
Highly Cited
2000
Vascular Endothelial Growth Factor (VEGF)-driven Actin-based Motility Is Mediated by VEGFR2 and Requires Concerted Activation of Stress-activated Protein Kinase 2 (SAPK2/p38) and Geldanamycin…
In endothelial cells, vascular endothelial growth factor (VEGF) induces an accumulation of stress fibers associated with new… Expand
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Review
1999
Review
1999
Regulation of actin dynamics by stress-activated protein kinase 2 (SAPK2)-dependent phosphorylation of heat-shock protein of 27 kDa (Hsp27).
Activation of the mitogen-activated protein kinase (MAP kinase) SAPK2 (stress-activated protein kinase 2) leads to the… Expand
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Highly Cited
1997
Highly Cited
1997
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases.
The paired helical filament, which comprises the major fibrous element of the neurofibrillary lesions of Alzheimer's disease, is… Expand
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Highly Cited
1997
Highly Cited
1997
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.
A cDNA was cloned that encodes human stress-activated protein kinase-4 (SAPK4), a novel MAP kinase family member whose amino acid… Expand
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Highly Cited
1997
Highly Cited
1997
Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38).
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution… Expand
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Highly Cited
1997
Highly Cited
1997
The p38/Reactivating Kinase Mitogen-activated Protein Kinase Cascade Mediates the Activation of the Transcription Factor Insulin Upstream Factor 1 and Insulin Gene Transcription by High Glucose in…
Insulin upstream factor 1 (IUF1), a transcription factor present in pancreatic β-cells, binds to the sequence C(C/T)TAATG present… Expand
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