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MAPK11 wt Allele

Known as: SAPK2B, PRKM11, SAPK2 
Human MAPK11 wild-type allele is located in the vicinity of 22q13.33 and is approximately 7 kb in length. This allele, which encodes mitogen… Expand
National Institutes of Health

Related topics

Related topics

17 relations
22q13.33Adipocytokine Signaling PathwayCell Cycle ControlMAPK Signaling Pathway
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Broader (1)

MAPK11 gene

Papers overview

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Highly Cited
2005
Highly Cited
2005
Generation and characterization of p38beta (MAPK11) gene-targeted mice.
p38 mitogen-activated protein kinases (MAPKs) are activated primarily in response to inflammatory cytokines and cellular stress… Expand
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Highly Cited
2005
Highly Cited
2005
Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization.
Antagonist studies show that spinal p38 mitogen-activated protein kinase plays a crucial role in spinal sensitization. However… Expand
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Highly Cited
2003
Highly Cited
2003
p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity.
p38 MAPK pathway signaling is known to participate in cell proliferation, apoptosis, and differentiation, in a manner dependent… Expand
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2000
2000
Constitutive activity and differential localization of p38alpha and p38beta MAPKs in adult mouse brain.
To understand the roles of p38 mitogen-activated protein kinase (p38 MAPK) isoforms in adult mouse brain, in vivo activities and… Expand
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Highly Cited
1999
Highly Cited
1999
Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages.
Four p38 mitogen-activated protein kinases (p38alpha, beta, gamma, delta) have been described. To understand the role of p38… Expand
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Highly Cited
1999
Highly Cited
1999
p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesis.
p38 mitogen-activated protein kinase (p38) has been extensively studied as a stress-responsive kinase, but its role in… Expand
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Highly Cited
1998
Highly Cited
1998
PRAK, a novel protein kinase regulated by the p38 MAP kinase.
We have identified and cloned a novel serine/ threonine kinase, p38-regulated/activated protein kinase (PRAK). PRAK is a 471… Expand
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Highly Cited
1998
Highly Cited
1998
Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.
Murine kidney cells of the inner medullary collecting duct (mIMCD) were exposed to either isosmotic (300 mosmol/kg) or… Expand
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Highly Cited
1997
Highly Cited
1997
Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles.
A novel homologue of p38 MAP kinase, called SAPK4, has been cloned which shares 61% amino acid identity with p38 and is expressed… Expand
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Highly Cited
1996
Highly Cited
1996
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta).
Mitogen-activated protein (MAP) kinase cascades represent one of the major signal systems used by eukaryotic cells to transduce… Expand
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