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Abstract Background and purpose PET with 18 F-Misonidazole (FMISO-PET) is a non-invasive method for measuring tumor hypoxia. We… Expand UNLABELLED
In radiotherapy of head and neck cancer (HNC) and non-small cell lung cancer (NSCLC), hypoxia is known to be an… Expand To correlate misonidazole concentrations and oxygen pressures (Po2) at identical locations within EMT6/Ro multi‐cell spheroids… Expand From 1979 through July 1983, 859 patients were enrolled in a Phase III RTOG Protocol (7916) evaluating the role of Misonidazole… Expand
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The cytotoxicities of a number of antineoplastic agents to oxygenated and hypoxic EMT6 mouse mammary tumor cells in culture were… Expand Abstract Using a combination of toxicological, pharmacological and radiosensitization experiments on cells in vitro and tumors in… Expand Ten 2-nitroimidazole radiosensitizers of electron affinity equal to that of misonidazole, but differing in their octanol:water… Expand Reduction of the nitro group occurred when [14C]misonidazole was treated with zinc dust in aqueous solution in the presence of… Expand Abstract The proportion of viable hypoxic cells in EMT6/St/lu tumours assayed 18 and 24 hours after a dose of misonidazole (1.2… Expand