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Misonidazole
Known as:
Misonidazole [Chemical/Ingredient]
, 1-(alpha-methoxymethyl ethanol)-2-Nitroimidazole
, alpha-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol
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A nitroimidazole with radiosensitizing and antineoplastic properties. Exhibiting high electron affinity, misonidazole induces the formation of free…
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National Institutes of Health
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Related topics
Related topics
26 relations
Narrower (12)
2-aminomisonidazole
4,5-dimethylmisonidazole
4-bromomisonidazole
RB 7040
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Broader (4)
Antineoplastic Agents
Antiprotozoal Agents
Imidazoles
Radiation-Sensitizing Agents
In Blood
NCIt Antineoplastic Agent Terminology
agonists
altretamine/cisplatin/cyclophosphamide/misonidazole protocol
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Papers overview
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1984
1984
Detection of a reactive metabolite of misonidazole in hypoxic mammalian cells.
A. J. Varghese
,
G. Whitmore
Radiation Research
1984
Corpus ID: 22190670
A misonidazole metabolite capable of reacting with guanosine has been detected in extracts of Chinese hamster ovary cells exposed…
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1984
1984
The effect of misonidazole as a hypoxic radiosensitizer at low dose.
B. Palcic
,
B. Faddegon
,
L. Skarsgard
Radiation Research
1984
Corpus ID: 35203086
Using an automated low dose survival assay, the radiosensitizing effectiveness of misonidazole at low radiation dose (0-6 Gy) was…
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1984
1984
Effect of Oxygen on Misonidazole Chemosensitization and Cytotoxicity in Vitro
Mulcahy Rt
1984
Corpus ID: 70574579
In order to assess the effect of oxygen on chemopotentiation by misonidazole (MISO), EMT-6/Ro tumor cells were exposed in vitro…
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1983
1983
Modification of stromal radiosensitivity by misonidazole and WR-2721.
A. Begg
,
N. Terry
British Journal of Radiology
1983
Corpus ID: 21471138
The radiosensitivity of normal vascular connective tissue has been assessed by measuring the growth rate of untreated tumours…
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1981
1981
The radiation reduction in misonidazole.
D. Whillans
,
G. Whitmore
Radiation Research
1981
Corpus ID: 5463190
[14C]Misonidazole, a 2-nitroimidazole radiation sensitizer, was reduced in dilute aqueous solution by irradiation in the absence…
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1981
1981
Modification of the oral radiation death syndrome with combined WR-2721 and misonidazole.
P. Grigsby
,
Y. Maruyama
British Journal of Radiology
1981
Corpus ID: 23868304
In order to investigate the combined use of radioprotective and radiosensitizing chemicals we have used WR--2721 and misonidazole…
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1981
1981
Radiation-enhanced cytotoxicity of misonidazole.
M. Korbelik
,
B. Palcic
,
L. Skarsgard
Radiation Research
1981
Corpus ID: 35379565
KORBELIK, M., PALCIC, B., AND SKARSGARD, L. D. Radiation-Enhanced Cytotoxicity of Misonidazole. Radiat. Res. 88, 343-353 (1981…
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1978
1978
Sensitizing and toxicity properties of misonidazole and its derivatives.
G. Whitmore
,
S. Gulyás
,
A. J. Varghese
The British journal of cancer. Supplement
1978
Corpus ID: 45527128
IN the early search for radiation sensitizers specific for hypoxic cells it was hoped that such compounds would mimic a number of…
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1978
1978
The toxicity of the radiosensitizer misonidazole towards hypoxic cells in vitro: a model for mouse and man.
I. Stratford
,
G. Adams
British Journal of Radiology
1978
Corpus ID: 29434300
The drug misonidazole, which is currently undergoing clinical trials as a radiosensitizer, has been shown to be much more toxic…
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1978
1978
Influence of tumour size on radiosensitization by misonidazole.
J. Stanley
,
M. Peckham
,
G. Steel
The British journal of cancer. Supplement
1978
Corpus ID: 7841206
The administration of misonidazole shortly before irradiation increased the radiation response of the Lewis lung tumour growing…
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