Microtubule-Organizing Center

Known as: microtubule organising centre, MTOC, Microtubule Organizing Center 
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
020406019732017

Related topics

Related topics

8 relations
CentrosomeMicrobiologicalProcess of secretionaspects of radiation effects
(More)

Narrower (2)

Kinetosome of ciliumequatorial microtubule organizing center

Broader (1)

Microtubule cytoskeleton

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Microtubule-Organizing Center
physiological aspects
Microbiological
Centrosome
Microtubule cytoskeleton
Kinetosome of cilium

Papers overview

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Highly Cited
2009
Highly Cited
2009
Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells
The reorientation of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting cell enables the directional… (More)
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Highly Cited
2004
Highly Cited
2004
Microtubule Nucleation at Non-Spindle Pole Body Microtubule-Organizing Centers Requires Fission Yeast Centrosomin-Related Protein mod20p
BACKGROUND Many types of differentiated eukaryotic cells display microtubule distributions consistent with nucleation from… (More)
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Highly Cited
1994
Highly Cited
1994
Pericentrin, a highly conserved centrosome protein involved in microtubule organization.
Antisera from scleroderma patients that react widely with centrosomes in plants and animals were used to isolate cDNAs encoding a… (More)
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Highly Cited
1991
Highly Cited
1991
The fission yeast gamma-tubulin is essential for mitosis and is localized at microtubule organizing centers.
gamma-Tubulin exists in fission yeast as the product of an essential gene, encoding a 446 amino acid protein that is 77.3… (More)
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Highly Cited
1985
Highly Cited
1985
Fate of microtubule-organizing centers during myogenesis in vitro
Microtubule organization and nucleation were studied during in vitro human myogenesis by immunocytology that used monoclonal and… (More)
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Highly Cited
1985
Highly Cited
1985
Non-spindle microtubule organizing centers in metaphase II-arrested mouse oocytes
A human autoantiserum (5051) directed against pericentriolar material (PCM) was used to study the distribution of microtubule… (More)
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Highly Cited
1984
Highly Cited
1984
Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells.
By immunofluorescence observations with cell couples of cloned murine cytotoxic T lymphocytes (CTL) and target cells, evidence is… (More)
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Highly Cited
1983
Highly Cited
1983
Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets.
In cell couples formed between a cloned murine natural killer (NK) cell and either of two target cells, we have obtained evidence… (More)
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Highly Cited
1982
Highly Cited
1982
Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells
Specific binding (conjugation) of cytotoxic T lymphocytes (CTL) to target cells (TC) is the first step in a multistage process… (More)
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Highly Cited
1981
Highly Cited
1981
Distribution of microtubule organizing centers in migrating sheets of endothelial cells
This study was designed to investigate the relationship between the position of the microtubule organizing center (MTOC) and the… (More)
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