FAQ

Methysergide

Known as: Metisergido, Methysergide [Chemical/Ingredient], methylsergide 
An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal… (More)

Topic mentions per year

Topic mentions per year

1950-2017
05010015019502016

Related topics

Related topics

31 relations
1-methyllysergic acid butanolamideArteriosclerosisAzolesBacterial Infections
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Broader (4)

ErgolinesSerotonin AntagonistsSerotonin Uptake InhibitorsVasoconstrictor Agents

Narrower (2)

SansertUML-491

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Methysergide
Hypertensive disease
Kidney Diseases
Drug Allergy
Lung diseases
Liver diseases

Papers overview

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Highly Cited
2006
Highly Cited
2006
Suppression of cortical spreading depression in migraine prophylaxis.
OBJECTIVE Topiramate, valproate, propranolol, amitriptyline, and methysergide have been widely prescribed for migraine… (More)
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Highly Cited
2006
Highly Cited
2006
EFNS guidelines on the treatment of cluster headache and other trigeminal-autonomic cephalalgias.
Cluster headache and the other trigeminal-autonomic cephalalgias [paroxysmal hemicrania, short-lasting unilateral neuralgiform… (More)
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Highly Cited
2000
Highly Cited
2000
Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications.
BACKGROUND Serotonergic medications with various mechanisms of action are used to treat psychiatric disorders and are being… (More)
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Highly Cited
1990
Highly Cited
1990
Free-choice responding for ethanol versus water in alcohol preferring (P) and unselected Wistar rats is differentially modified by naloxone, bromocriptine, and methysergide
The role of opioids, dopamine and serotonin in ethanol (EtOH) reward and preference was investigated in non-deprived, Alcohol… (More)
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Highly Cited
1990
Highly Cited
1990
Noradrenergic and serotonergic modulation of a hyperpolarization-activated cation current in thalamic relay neurones.
1. Modulation of the hyperpolarization-activated cation current, Ih, by noradrenaline (NA) and serotonin (5-HT) was examined in… (More)
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Highly Cited
1989
Highly Cited
1989
Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists.
Intrathecal administration of glycine (strychnine) or GABA (bicuculline) but not opioid (naloxone), adrenergic (phentolamine) or… (More)
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Highly Cited
1989
Highly Cited
1989
Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential.
1. The effect of serotonin on the firing properties of motoneurones was studied in transverse sections of the adult turtle spinal… (More)
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1988
1988
Methysergide potentiates the hyperactivity produced by MDMA in rats.
Although some substituted amphetamines, like MDA, produce a combination of sympathomimetic stimulation and perceptual alterations… (More)
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1986
1986
Pharmacokinetics of methysergide and its metabolite methylergometrine in man
Five healthy men were given 1.0 mg methysergide maleate intravenously and 2.7 mg methysergide maleate orally in a cross-over… (More)
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Highly Cited
1979
Highly Cited
1979
Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation
1. Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous nerve in… (More)
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