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Methysergide

Known as: Metisergido, Methysergide [Chemical/Ingredient], methylsergide 
An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal… 
National Institutes of Health

Related topics

Related topics

30 relations
1-methyllysergic acid butanolamideArteriosclerosisAzolesBacterial Infections

Broader (4)

ErgolinesSerotonin AntagonistsSerotonin Uptake InhibitorsVasoconstrictor Agents

Narrower (3)

Methysergide MaleateSansertUML-491

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Methysergide‐induced scleroderma‐like changes of the legs
SIR, Methysergide is a semisynthetic ergot alkaloid ergometrine derivative, acting as a serotonin receptor antagonist, used in… 
1986
1986
Effects of methysergide on the cough reflex.
The present study had two basic purposes: to observe the effect of methysergide on the cough reflex and to investigate the effect… 
Highly Cited
1982
Highly Cited
1982
Pharmacological effects of peptides on tracheal smooth muscle.
Peptide and non-peptide agents were tested for their stimulatory or inhibitory effects on circular strips of guinea pig isolated… 
1981
1981
Intralimbic progesterone and methysergide facilitate lordotic behavior in estrogen-primed female rats.
Intracranial administration of progesterone or a serotonergic receptor blocker into either the dorsal hippocampus or… 
1978
1978
Prolactin suppression by serotonin antagonists in man: further evidence for serotoninergic control of prolactin secretion.
To further investigate the role of serotonin in human prolactin (Prl) secretion, serotonin antagonists have been administered to… 
1975
1975
AN UNEXPECTED EFFECT OF SEROTONIN ANTAGONISTS ON THE CANINE NASAL CIRCULATION
SYNOPSIS 
1974
1974
Part 2" In vitro contractile activity of serotonin in human serum and CSF on the canine basilar artery, and its blockage by methylsergide and phenoxybenzamine
In vitro experiments were performed to determine the contractile activity of human serum and cerebrospinal fluid on the canine… 
1972
1972
Observations on the use of methysergide in Huntington's chorea
Although the pathological alteration of the striatum in Huntington’s chorea has been known for years’ ,’ the physiologic… 
1971
1971
FIBROTIC SYNDROMES WITH CHRONIC USE OF METHYSERGIDE
METHYSERGIDE, BETTER known as Sansert or Deseril, has been used for the prophylactic treatment of migraine and other vascular… 
1970
1970
Methysergide as a treatment for mania.
Reports of dramatically successful treatment of acute mania with methysergide led the authors to undertake a small study. Twelve…