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Methylnitrosourea

Known as: methylnitrosourea (MNU), NMH, N Methyl N nitrosourea 
A pale yellow, crystalline nitrosourea that is sensitive to light and moisture and emits toxic fumes of nitrogen oxides when heated to decomposition… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (6)

ADEKON,N'-dimethylnitrosoureaN-trimethylsilylmethyl-N-nitrosoureaNSC-23909

Broader (3)

Alkylating AgentsCarcinogensNitrosourea Compounds
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
A Review of Animal Model Studies of Tomato Carotenoids, Lycopene, and Cancer Chemoprevention
There are relatively few reports on the cancer chemopreventive effects of lycopene or tomato carotenoids in animal models. The… 
Highly Cited
1998
Highly Cited
1998
Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats.
One of the most consistent results in the epidemiology of human breast cancer is the inverse relationship of risk and early full… 
Highly Cited
1997
Highly Cited
1997
Allium cepa anaphase-telophase root tip chromosome aberration assay on N-methyl-N-nitrosourea, maleic hydrazide, sodium azide, and ethyl methanesulfonate.
Highly Cited
1996
Highly Cited
1996
Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones.
Soy-based diets, rich in the isoflavones genistein and daidzein, are thought to protect against breast and prostate cancer. We… 
Review
1993
Review
1993
A review of the genotoxicity of 1-ethyl-1-nitrosourea.
Highly Cited
1974
Highly Cited
1974
The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.
Highly Cited
1973
Highly Cited
1973
Patterns of damage and repair of liver DNA induced by carcinogenic methylating agents in vivo.
Single-strand breaks induced by methylating agents in liver DNA and their rejoining were studied in vivo by the use of alkaline… 
Highly Cited
1971
Highly Cited
1971
Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells. I. The effect on HeLa and Chinese hamster cell survival of alkylation of cellular macromolecules.
Highly Cited
1971
Highly Cited
1971
Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells. II. Non-semiconservative DNA synthesis ('repair synthesis') in HeLa and Chinese hamster cells following treatment with…
Highly Cited
1969
Highly Cited
1969
Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents
The system previously described for inducing single gene mutations in Chinese hamster cells has been extended to produce… 
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