Methyl Group

A small molecule made of one carbon and three hydrogen atoms. Methyl groups are added or removed from proteins or nucleic acids and may change the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Although inhibitors of the renin-angiotensin-aldosterone system can slow the progression of diabetic kidney disease… (More)
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Highly Cited
2011
Highly Cited
2011
Enzymes catalysing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression and… (More)
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Review
2010
Review
2010
Betaine is an essential osmolyte and source of methyl groups and comes from either the diet or by the oxidation of choline. Its… (More)
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Review
2009
Review
2009
The covalent marking of proteins by methyl group addition to arginine residues can promote their recognition by binding partners… (More)
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Highly Cited
2006
Highly Cited
2006
microRNAs (miRNAs) and small interfering RNAs (siRNAs) in plants bear a methyl group on the ribose of the 3' terminal nucleotide… (More)
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Highly Cited
2005
Highly Cited
2005
Small RNAs of 21-25 nucleotides (nt), including small interfering RNAs (siRNAs) and microRNAs (miRNAs), act as guide RNAs to… (More)
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Highly Cited
2002
Highly Cited
2002
Aberrant DNA methylation is recognized as being a common feature of human neoplasia.CpG island hypermethylation and global… (More)
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Review
1996
Review
1996
S-Adenosylmethionine (AdoMet or SAM) plays a pivotal role as a methyl donor in a myriad of biological and biochemical events… (More)
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Highly Cited
1985
Highly Cited
1985
The interaction of a probe group with a protein of known structure is computed at sample positions throughout and around the… (More)
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Highly Cited
1982
Highly Cited
1982
Incubation of DNA with S-adenosyl-L-methionine (SAM) in neutral aqueous solution leads to base modification, with formation of… (More)
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