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Metallothionein

Known as: Metallothionein [Chemical/Ingredient], Metallothioneins 
A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains… 
National Institutes of Health

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Narrower (29)

CUP1-1 protein, S cerevisiaeCUP1-2 protein, S cerevisiaeCd-Zn-metallothioneinHg-Cu-metallothionein
In BloodLigand BindingMT4 geneMetal Ion Binding

Broader (1)

Metalloproteins

Papers overview

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2005
2005
The Cd-Chelex assay: A new sensitive method to determine metallothionein containing zinc and cadmium
A rapid and sensitive one-vial procedure to determine metallothionein (MT) containing zinc (Zn) and cadmium (Cd) is described… 
1988
1988
Differential expression of four linked sheep metallothionein genes.
Regulation of the closely linked endogenous sheep MT-Ia, MT-Ib, MT-Ic and MT-II genes by heavy metals and dexamethasone was… 
1986
1986
Interaction of metallothionein and carbon tetrachloride on the protective effect of zinc on hepatotoxicity.
To study the influence of hepatic metallothionein (MT) on the hepatotoxic response to carbon tetrachloride (CCl4), adult male… 
1986
1986
Structure of the copper cluster in canine hepatic metallothionein using X-ray absorption spectroscopy.
The metal binding site in the lysosomal copper metallothionein from canine liver (LyCuLP) was examined with X-ray edge and… 
1985
1985
Studies on the metabolism of rat liver copper-metallothionein.
The degradation of purified 35S-labelled rat liver isometallothioneins (MT) by lysosomal extracts was studied. Zn-MT-I was more… 
Highly Cited
1983
Highly Cited
1983
Increased metallothionein content in rat liver induced by X irradiation and exposure to high oxygen tension.
X irradiation and exposure to high oxygen tension are known to induce lipid peroxidation. The effects of these stresses on… 
Highly Cited
1983
Highly Cited
1983
Characterization of isoprotein patterns in tissue extracts and isolated samples of metallothioneins by reverse-phase high-pressure liquid chromatography.
Reverse-phase high-pressure ('performance') liquid chromatography was used to characterize the isometallothioneins in… 
Highly Cited
1981
Highly Cited
1981
On the reactivity of metallothioneins with 5,5'-dithiobis-(2-nitrobenzoic acid).
Rat liver and horse kidney metallothioneins react with 5,5'-dithiobis-(2-nitrobenzoic acid) (Nbs2) to release 5-thio-2… 
Highly Cited
1978
Highly Cited
1978
Cell-free synthesis of metallothionein directed by rat liver polyadenylated messenger ribonucleic acid.
Total RNA was isolated from rat liver polyribosomes and fractionated by oligo(dT)-cellulose chromatography to obtain… 
Highly Cited
1977
Highly Cited
1977
A modified procedure for determination of metallothionein-like proteins in animal tissues.
: 1. The effect of low-molecular-weight substances interfering with determination of metallothionein is eliminated by…