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Megestrol Acetate

Known as: 6-Methyl-delta-4,6-pregnadien-17 alpha-ol-3,20-dione Acetate, 17alpha-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17?-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate 
The acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic… 
National Institutes of Health

Related topics

Related topics

28 relations
AnorexiaCachexiaDrug AllergyEndometrial Neoplasms

Broader (3)

Antineoplastic Agents, HormonalAppetite StimulantsMegestrol

Narrower (5)

BoreaMegaceMestrelNiagestin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Pluronic block copolymers and Pluronic poly(acrylic acid) microgels in oral delivery of megestrol acetate
Several Pluronic‐based formulations were studied in‐vitro and in a rat model with respect to the release and bioavailability of… 
Review
2002
Review
2002
Treating malnutrition with megestrol acetate: literature review and review of our experience.
Megestrol acetate is a semi-synthetic progestational steroid that was originally used as a therapeutic modality for metastatic… 
Highly Cited
2001
Highly Cited
2001
The correlation of cytokine levels with body weight after megestrol acetate treatment in geriatric patients.
BACKGROUND Cachexia is associated with elevated levels of cytokines in cancer and human immunodeficiency virus patients. Studies… 
Highly Cited
1998
Highly Cited
1998
The dynamics of prostate specific antigen in hormone refractory prostate carcinoma
Although many physicians measure serum prostate specific antigen (PSA) during the follow‐up of patients with hormone refractory… 
Review
1995
Review
1995
The Literature of Medicine: Reviews and Notes: Clinical Disturbances of Water Metabolism; and Clinical Disorders of Fluid and Electrolyte Metabolism
Correction: Copyright Date A review of the book Clinical Disorders of Fluid and Electrolyte Metabolism (RG Narins, ed… 
Highly Cited
1994
Highly Cited
1994
A prospective comparison of treatments for symptomatic hot flushes following endocrine therapy for carcinoma of the prostate.
Review
1993
Review
1993
Rapid non-genomic actions of progesterone stimulate Ca2+ influx and the acrosome reaction in human sperm.
Highly Cited
1980
Highly Cited
1980
Progestin therapy in advanced breast cancer: Megestrol acetate—an evaluation of 160 treated cases
Progestin megestrol acetate treatment of 160 postmenopausal women with progressive metastatic breast cancer is evaluated… 
Highly Cited
1976
Highly Cited
1976
Effect of megestrol acetate (Megace) on steroid metabolism and steroid-protein binding in the human prostate.
Megestrol acetate (Megace), an antiandrogen, was administered in a dosage of 80 mg daily to 6 patients with benign prostatic… 
Highly Cited
1969
Highly Cited
1969
Fertility control in women with a progestogen released in microquantities from subcutaneous capsules.
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