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Megestrol Acetate

Known as: 6-Methyl-delta-4,6-pregnadien-17 alpha-ol-3,20-dione Acetate, 17alpha-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17?-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate 
The acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
BACKGROUND Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer-associated anorexia. In… 
Highly Cited
2004
Highly Cited
2004
PURPOSE Studies suggest eicosapentaenoic acid (EPA), an omega-3 fatty acid, augments weight, appetite, and survival in cancer… 
Review
2003
Review
2003
Highly Cited
2002
Highly Cited
2002
PURPOSE To determine whether dronabinol administered alone or with megestrol acetate was more, less, or equal in efficacy to… 
Review
2002
Review
2002
  • A. Inui
  • CA: a cancer journal for clinicians
  • 2002
  • Corpus ID: 29298459
Cachexia is among the most debilitating and life‐threatening aspects of cancer. Associated with anorexia, fat and muscle tissue… 
Highly Cited
2001
Highly Cited
2001
PURPOSE To compare two doses of letrozole (0.5 mg and 2.5 mg every day) and megestrol acetate (40 mg qid) as endocrine therapy in… 
Highly Cited
2000
Highly Cited
2000
PURPOSE This phase III, double-blind, randomized, multicenter study evaluated the efficacy, pharmacodynamics, and safety of the… 
Highly Cited
1999
Highly Cited
1999
PURPOSE Previous double-blind, placebo-controlled, randomized clinical trials have demonstrated that both corticosteroids and… 
Highly Cited
1998
Highly Cited
1998
PURPOSE To compare two doses of letrozole and megestrol acetate (MA) as second-line therapy in postmenopausal women with advanced… 
Highly Cited
1998
Highly Cited
1998
This report presents the results of a survival update based on the combined data from two studies that compared the efficacy and…