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Mechlorethamine hydrochloride

Known as: Chloromethine HCl, Methylbis(beta-chloroethyl)amine Hydrochloride, ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl Hydrochloride 
The hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities… 
National Institutes of Health

Related topics

Related topics

33 relations
Alkylating Activity [MoA]Communicable DiseasesCyclophosphamide/Mechlorethamine/Prednisone/Procarbazine/Vincristine protocolDrug Allergy

Narrower (4)

CaryolysineCloraminErasolMustargen

Broader (2)

Mustard CompoundsNitrogen Mustard Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Early and Late Effects of Leukopenic Reperfusion on the Recovery of Cardiac Contractile Function Studies in the Transplanted and Isolated Blood‐Perfused Rat Heart
BackgroundSince there is considerable evidence that leukocytes contribute to tissue injury during ischemia and reperfusion, the… 
1990
1990
The radiation therapy of early stage cutaneous T-cell lymphoma.
1981
1981
Rat conceptus development in vitro: comparative effects of alkylating agents.
1975
1975
The Effect of Cytotoxic and Anti‐inflammatory Drugs on the Phagocytosis of Neutrophil Leucocytes
Summary. The phagocytosis of heat‐killed Candida albicans by neutrophil leucocytes was inhibited in vitro by phenylbutazone and… 
1975
1975
Mechlorethamine desensitization in therapy for mycosis fungoides. Topical desensitization to mechlorethamine (nitrogen mustard) contact hypersensitivity.
Five patients with mycosis fungoides who had developed contact dermatitis to a nitrogen mustard, mechlorethamine hydrochloride… 
1971
1971
Topically applied mechlorethamine in the treatment of psoriasis.
The psoriatic lesions of seven male patients were treated with a daily topical application of 10 mg of mechlorethamine… 
1970
1970
Effects of topical mechlorethamine on skin lesions of psoriasis.
Topical applications of aqueous solutions of mechlorethamine hydrochloride were given to 12 patients with resistant psoriasis… 
1965
1965
Bronchial Carcinoma Treated with Nitrogen Mustard and Cyclophosphamide
Nitrogen mustard (mustine hydrochloride) has been used in the treatment of lung cancer for 20 years. Lynch, Ware, and Gaensler… 
1962
1962
Topically Applied Mechlorethamine on 12 Dermatoses
In 1959 remission occurred in a case of mycosis fungoides following the topical application of mechlorethamine hydrochloride (a… 
1958
1958
Emetic action of nitrogen mustard (mechlorethamine hydrochloride) in dogs and cats.
The early emetic response (within 4 hr.) after intravenous injection of the nitrogen mustard, methyl-bis (beta-chlorethyl) amine… 
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