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Mechlorethamine hydrochloride
Known as:
Chloromethine HCl
, Methylbis(beta-chloroethyl)amine Hydrochloride
, ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl Hydrochloride
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The hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities…
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National Institutes of Health
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Related topics
Related topics
33 relations
Alkylating Activity [MoA]
Communicable Diseases
Cyclophosphamide/Mechlorethamine/Prednisone/Procarbazine/Vincristine protocol
Drug Allergy
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Narrower (4)
Caryolysine
Cloramin
Erasol
Mustargen
Broader (2)
Mustard Compounds
Nitrogen Mustard Compounds
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis…
S. Lessin
,
M. Duvic
,
+14 authors
Youn H. Kim
JAMA dermatology
2013
Corpus ID: 13599249
OBJECTIVE To evaluate the efficacy and safety of a novel mechlorethamine hydrochloride, 0.02%, gel in mycosis fungoides. DESIGN…
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Review
2011
Review
2011
Extravasation management: clinical update.
L. Schulmeister
Seminars in Oncology Nursing
2011
Corpus ID: 41819901
Highly Cited
2008
Highly Cited
2008
Phase II multicenter study of bendamustine plus rituximab in patients with relapsed indolent B-cell and mantle cell non-Hodgkin's lymphoma.
K. Robinson
,
Michael E. Williams
,
+6 authors
B. Cheson
Journal of Clinical Oncology
2008
Corpus ID: 23801856
PURPOSE Bendamustine HCl is a bifunctional mechlorethamine derivative with clinical activity in the treatment of non-Hodgkin's…
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Highly Cited
1996
Highly Cited
1996
Clinical stage IA (limited patch and plaque) mycosis fungoides. A long-term outcome analysis.
Y. Kim
,
R. Jensen
,
G. Watanabe
,
A. Varghese
,
R. Hoppe
Archives of Dermatology
1996
Corpus ID: 37650752
OBJECTIVES To study the long-term results of treatment of patients with stage IA mycosis fungoides and analyze the factors…
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Review
1992
Review
1992
The molecular pharmacology of L-deprenyl.
M. Gerlach
,
P. Riederer
,
M. Youdim
European Journal of Pharmacology
1992
Corpus ID: 25711356
Highly Cited
1989
Highly Cited
1989
Induction of fos RNA by DNA-damaging agents.
M. C. Hollander
,
A. Fornace
Cancer Research
1989
Corpus ID: 38822270
We have found that a wide variety of DNA-damaging agents and heat shock increase fos RNA to different extents in Chinese hamster…
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Highly Cited
1988
Highly Cited
1988
Topical mechlorethamine therapy for early stage mycosis fungoides.
D. Ramsay
,
P. Halperin
,
A. Zeleniuch‐Jacquotte
Journal of American Academy of Dermatology
1988
Corpus ID: 4854768
Highly Cited
1985
Highly Cited
1985
Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit.
S. Holdsworth
,
P. Tipping
Journal of Clinical Investigation
1985
Corpus ID: 23121385
Glomerular fibrin deposition is important in the pathogenesis of renal failure and crescent formation in glomerulonephritis. The…
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Highly Cited
1981
Highly Cited
1981
Leukocytes Are Required for Increased Lung Microvascular Permeability after Microembolization in Sheep
M. R. Flick
,
A. Perel
,
N. Staub
Circulation Research
1981
Corpus ID: 14691702
We studied the effects of uneven pulmonary artery obstruction by microemboli on steady state transvascular fluid and protein…
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Highly Cited
1970
Highly Cited
1970
Combination Chemotherapy in Generalized Hodgkin's Disease
W. Nicholson
,
M. Beard
,
+5 authors
R. Scott
British medical journal
1970
Corpus ID: 43434367
Fifty-two patients with generalized Hodgkin's disease were treated with a combination of mustine hydrochloride, vinblastine…
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