Mechlorethamine hydrochloride

Known as: Chloromethine HCl, Methylbis(beta-chloroethyl)amine Hydrochloride, ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl Hydrochloride 
The hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities… (More)
National Institutes of Health

Related topics

Related topics

32 relations
Alkylating Activity [MoA]Communicable DiseasesCyclophosphamide/Mechlorethamine/Prednisone/Procarbazine/Vincristine protocolDrug Allergy
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Narrower (4)

CaryolysineCloraminErasolMustargen

Broader (2)

Mustard CompoundsNitrogen Mustard Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Phase I/II trial assessing bendamustine plus bortezomib combination therapy for the treatment of patients with relapsed or refractory multiple myeloma.
Bendamustine, active in multiple myeloma (MM), is a bifunctional mechlorethamine derivative with alkylating properties… (More)
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Review
2011
Review
2011
Extravasation management: clinical update.
OBJECTIVE To present a clinical update on the prevention, detection, and evidence-based management of vesicant chemotherapy… (More)
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Highly Cited
2008
Highly Cited
2008
Phase II multicenter study of bendamustine plus rituximab in patients with relapsed indolent B-cell and mantle cell non-Hodgkin's lymphoma.
PURPOSE Bendamustine HCl is a bifunctional mechlorethamine derivative with clinical activity in the treatment of non-Hodgkin's… (More)
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1998
1998
Stability of mechlorethamine hydrochloride 0.01% ointment in aquaphor base.
The purpose of this project was to evaluate the short-term shelf-life stability of an extemporaneously compounded mechlorethamine… (More)
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1996
1996
A novel DNA damage-inducible transcript, gadd7, inhibits cell growth, but lacks a protein product.
gadd7 cDNA was isolated from Chinese hamster ovary (CHO) cells on the basis of increased levels of RNA following treatment with… (More)
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Highly Cited
1996
Highly Cited
1996
Clinical stage IA (limited patch and plaque) mycosis fungoides. A long-term outcome analysis.
OBJECTIVES To study the long-term results of treatment of patients with stage IA mycosis fungoides and analyze the factors… (More)
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1988
1988
Topical mechlorethamine therapy for early stage mycosis fungoides.
One hundred seventeen patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride. The probability of… (More)
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1985
1985
Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit.
Glomerular fibrin deposition is important in the pathogenesis of renal failure and crescent formation in glomerulonephritis. The… (More)
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1985
1985
Further experience of Corynebacterium parvum in malignant pleural effusion.
The outcome of drug induced pleurodesis has been evaluated in a non-randomised retrospective study of 67 patients with recurrent… (More)
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1983
1983
Second cancers after radiotherapy and chemotherapy for early stages of Hodgkin's disease.
In a population of 334 patients treated for Hodgkin's disease by the European Organization for Research and Treatment of Cancer… (More)
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