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Mechlorethamine hydrochloride
Known as:
Chloromethine HCl
, Methylbis(beta-chloroethyl)amine Hydrochloride
, ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl Hydrochloride
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The hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities…
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National Institutes of Health
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Related topics
Related topics
33 relations
Alkylating Activity [MoA]
Communicable Diseases
Cyclophosphamide/Mechlorethamine/Prednisone/Procarbazine/Vincristine protocol
Drug Allergy
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Narrower (4)
Caryolysine
Cloramin
Erasol
Mustargen
Broader (2)
Mustard Compounds
Nitrogen Mustard Compounds
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
A novel DNA damage-inducible transcript, gadd7, inhibits cell growth, but lacks a protein product.
M. Hollander
,
I. Alamo
,
A. Fornace
Nucleic Acids Research
1996
Corpus ID: 16945366
gadd7 cDNA was isolated from Chinese hamster ovary (CHO) cells on the basis of increased levels of RNA following treatment with…
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1993
1993
Early and Late Effects of Leukopenic Reperfusion on the Recovery of Cardiac Contractile Function Studies in the Transplanted and Isolated Blood‐Perfused Rat Heart
M. Galifianes
,
C. Lawson
,
R. Ferrari
,
G. Limb
,
N. Derias
,
D. Hearse
Circulation
1993
Corpus ID: 2424080
BackgroundSince there is considerable evidence that leukocytes contribute to tissue injury during ischemia and reperfusion, the…
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1990
1990
The radiation therapy of early stage cutaneous T-cell lymphoma.
B. Micaily
,
C. Moser
,
+4 authors
L. Brady
International Journal of Radiation Oncology…
1990
Corpus ID: 23384747
1981
1981
Rat conceptus development in vitro: comparative effects of alkylating agents.
M. K. Sanyal
,
K. Kitchin
,
R. Dixon
Toxicology and Applied Pharmacology
1981
Corpus ID: 34730609
1975
1975
The Effect of Cytotoxic and Anti‐inflammatory Drugs on the Phagocytosis of Neutrophil Leucocytes
J. Whittaker
,
H. Hughes
,
M. Khurshid
British Journal of Haematology
1975
Corpus ID: 29532760
Summary. The phagocytosis of heat‐killed Candida albicans by neutrophil leucocytes was inhibited in vitro by phenylbutazone and…
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1975
1975
Mechlorethamine desensitization in therapy for mycosis fungoides. Topical desensitization to mechlorethamine (nitrogen mustard) contact hypersensitivity.
V. S. Constantine
,
Z. Fuks
,
E. Farber
Archives of Dermatology
1975
Corpus ID: 22792791
Five patients with mycosis fungoides who had developed contact dermatitis to a nitrogen mustard, mechlorethamine hydrochloride…
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1971
1971
Topically applied mechlorethamine in the treatment of psoriasis.
S. Mandy
,
J. Taylor
,
K. Halprin
Archives of Dermatology
1971
Corpus ID: 37520693
The psoriatic lesions of seven male patients were treated with a daily topical application of 10 mg of mechlorethamine…
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1970
1970
Effects of topical mechlorethamine on skin lesions of psoriasis.
E. Epstein
,
A. R. Ugel
Archives of Dermatology
1970
Corpus ID: 26546877
Topical applications of aqueous solutions of mechlorethamine hydrochloride were given to 12 patients with resistant psoriasis…
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1965
1965
Bronchial Carcinoma Treated with Nitrogen Mustard and Cyclophosphamide
K. M. Barran
,
W. Helm
,
D. A. King
British medical journal
1965
Corpus ID: 26622864
Nitrogen mustard (mustine hydrochloride) has been used in the treatment of lung cancer for 20 years. Lynch, Ware, and Gaensler…
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1958
1958
Emetic action of nitrogen mustard (mechlorethamine hydrochloride) in dogs and cats.
H. L. Borison
,
E. Brand
,
R. Orkand
American Journal of Physiology
1958
Corpus ID: 26998857
The early emetic response (within 4 hr.) after intravenous injection of the nitrogen mustard, methyl-bis (beta-chlorethyl) amine…
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