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Maturation-Promoting Factor

Known as: MPF, M-Phase-Promoting Factor, M Phase Promoting Factor 
M Phase-Promoting Factor is a protein kinase complex that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
A period of oocyte growth is followed by a process called oocyte maturation (the resumption of meiosis) which occurs prior to… Expand
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Highly Cited
2002
Highly Cited
2002
The nuclei of early syncytial Drosophila embryos migrate dramatically toward the poles. The cellular mechanisms driving this… Expand
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Highly Cited
1999
Highly Cited
1999
Polo kinases execute multiple roles during cell division. The fission yeast polo related kinase Plo1 is required to assemble the… Expand
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Highly Cited
1992
Highly Cited
1992
M phase promoting factor (MPF) is a major element controlling entry into the M phase of the eukaryotic cell cycle. MPF is… Expand
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Highly Cited
1991
Highly Cited
1991
We have used immunofluorescence staining to study the subcellular distribution of cyclin A and B1 during the somatic cell cycle… Expand
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Highly Cited
1990
Highly Cited
1990
Highly purified maturation-promoting factor (MPF) from Xenopus eggs contains both cyclin B1 and cyclin B2 as shown by Western… Expand
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Highly Cited
1990
Highly Cited
1990
CYCLINS are proteins synthesized during each cell cycle and abruptly destroyed in each mitosis1–5. Cyclins have been implicated… Expand
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Highly Cited
1989
Highly Cited
1989
We show that cyclin plays a pivotal role in the control of mitosis. A proteolysis-resistant mutant of cyclin prevents the… Expand
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Highly Cited
1988
Highly Cited
1988
Maturation-promoting factor causes germinal vesicle breakdown when injected into Xenopus oocytes and can induce metaphase in a… Expand
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Highly Cited
1971
Highly Cited
1971
Fully grown oocytes of the frog (Rana pipiens) undergo cytoplasmic and nuclear maturation when treated with progesterone after… Expand
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