FAQ

Maturation-Promoting Factor

Known as: MPF, M-Phase-Promoting Factor, M Phase Promoting Factor 
M Phase-Promoting Factor is a protein kinase complex that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it… (More)

Topic mentions per year

Topic mentions per year

1978-2018
02419782018

Related topics

Related topics

23 relations
CDC2 Protein KinaseChromosome CondensationCyclin B1Cyclins
(More)

Broader (1)

Cell Cycle Proteins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Maturation-Promoting Factor
physiological aspects
agonists
Mitosis
Homo sapiens
Proliferating Cell Nuclear Antigen

Papers overview

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2013
2013
Serum folate receptor alpha, mesothelin and megakaryocyte potentiating factor in ovarian cancer: association to disease stage and grade and comparison to CA125 and HE4
BACKGROUND Evaluate and compare the utility of serum folate receptor alpha (FRA) and megakaryocyte potentiating factor (MPF… (More)
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2009
2009
Kinase-dependent regulation of inositol 1,4,5-trisphosphate-dependent Ca2+ release during oocyte maturation.
Fertilization induces a species-specific Ca(2+) transient with specialized spatial and temporal dynamics, which are essential to… (More)
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2008
2008
Differential phosphorylation of Cdc25C phosphatase in mitosis.
Cdc25 dual-specificity phosphatases coordinate entry into mitosis through activating dephosphorylation of the Mitosis-Promoting… (More)
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2006
2006
The C. elegans Myt1 ortholog is required for the proper timing of oocyte maturation.
Maturation promoting factor (MPF), a complex of cyclin-dependent kinase 1 and cyclin B, drives oocyte maturation in all animals… (More)
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Highly Cited
2003
Highly Cited
2003
Metaphase I Arrest upon Activation of the Mad2-Dependent Spindle Checkpoint in Mouse Oocytes
BACKGROUND The importance of mitotic spindle checkpoint control has been well established during somatic cell divisions. The… (More)
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2001
2001
New B-type cyclin synthesis is required between meiosis I and II during Xenopus oocyte maturation.
Progression through meiosis requires two waves of maturation promoting factor (MPF) activity corresponding to meiosis I and… (More)
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2000
2000
Nuclei and Microtubule Asters Stimulate Maturation/M Phase Promoting Factor (Mpf) Activation in Xenopus Eggs and Egg Cytoplasmic Extracts
Although maturation/M phase promoting factor (MPF) can activate autonomously in Xenopus egg cytoplasm, indirect evidence suggests… (More)
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Highly Cited
1996
Highly Cited
1996
Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast
BACKGROUND Mitosis is regulated by MPF (maturation promoting factor), the active form of Cdc2/28-cyclin B complexes. Increasing… (More)
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Highly Cited
1994
Highly Cited
1994
Microtubule and chromatin behavior follow MAP kinase activity but not MPF activity during meiosis in mouse oocytes.
Oocyte meiotic maturation is triggered by different stimuli (hormones, unknown signals through cell interactions) in different… (More)
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1978
1978
Method for the preparation of active maturation promoting factor (MPF) from in vitro matured oocytes of Xenopus laevis.
  • Karen Drury
  • Differentiation; research in biological diversity
  • 1978
A method for the large scale extraction of Maturation Promoting Factor (MPF) from in vitro matured oocytes of Xenopus laevis is… (More)
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