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Maturation-Promoting Factor

Known as: MPF, M-Phase-Promoting Factor, M Phase Promoting Factor 
M Phase-Promoting Factor is a protein kinase complex that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
A period of oocyte growth is followed by a process called oocyte maturation (the resumption of meiosis) which occurs prior to… Expand
Highly Cited
1998
Highly Cited
1998
A.Hagting and C.Karlsson contributed equally to this work 
Highly Cited
1991
Highly Cited
1991
We have used immunofluorescence staining to study the subcellular distribution of cyclin A and B1 during the somatic cell cycle… Expand
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Highly Cited
1990
Highly Cited
1990
Highly purified maturation-promoting factor (MPF) from Xenopus eggs contains both cyclin B1 and cyclin B2 as shown by Western… Expand
Highly Cited
1990
Highly Cited
1990
CYCLINS are proteins synthesized during each cell cycle and abruptly destroyed in each mitosis1–5. Cyclins have been implicated… Expand
Highly Cited
1989
Highly Cited
1989
We show that cyclin plays a pivotal role in the control of mitosis. A proteolysis-resistant mutant of cyclin prevents the… Expand
Highly Cited
1989
Highly Cited
1989
In the clam, Spisula, two previously described proteins known as cyclin A and B display the unusual property of selective… Expand
Highly Cited
1988
Highly Cited
1988
Maturation-promoting factor causes germinal vesicle breakdown when injected into Xenopus oocytes and can induce metaphase in a… Expand
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Highly Cited
1988
Highly Cited
1988
During mouse oocyte maturation the regulation of the activity of a cytoplasmic maturation-promoting factor (MPF) was examined… Expand
Highly Cited
1971
Highly Cited
1971
Fully grown oocytes of the frog (Rana pipiens) undergo cytoplasmic and nuclear maturation when treated with progesterone after… Expand