Matrix Metalloproteinase 13

Known as: Metalloproteinase, MMP13, Metalloproteinase-13, Matrix, Collagenase 3 
A secreted matrix metalloproteinase that plays a physiological role in the degradation of extracellular matrix found in skeletal tissues. It is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Experimental evidence suggests that matrix metalloproteinase-13 (MMP-13) protein may promote breast tumor progression, however… (More)
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2005
2005
Chondrocyte anabolic activity has been shown to decline with aging, but catabolic activity has received little attention. In this… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Rotator cuff tears are a cause of pain and disability in the shoulder. The molecular changes associated with rotator… (More)
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2004
2004
We have demonstrated previously that new blood vessel formation induced by angiogenic growth factors in onplants placed on the… (More)
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Highly Cited
2003
Highly Cited
2003
Tumor necrosis factor alpha (TNF-alpha), a major proinflammatory cytokine, induces arthritic joint inflammation and resorption of… (More)
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Highly Cited
2001
Highly Cited
2001
It has been suggested that increased collagenase-3 (MMP-13) activity plays a pivotal role in the pathogenesis of osteoarthritis… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Several recent studies attempted to classify plaques as those prone to cause clinical manifestations (vulnerable… (More)
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Highly Cited
1997
Highly Cited
1997
Squamous cell carcinomas (SCCs) of the head and neck are malignant tumors with high capacity to invade and metastasize. We have… (More)
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Highly Cited
1997
Highly Cited
1997
Collagenase-3 (MMP-13) is a novel matrix metalloproteinase, the expression of which has so far only been documented in human… (More)
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Highly Cited
1996
Highly Cited
1996
Degradation of the large cartilage proteoglycan aggrecan in arthritis involves an unidentified enzyme aggrecanase, and at least… (More)
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