MMP13 protein, human

Known as: CLG3 protein, human, Matrix Metalloprotease 13, Matrix Metalloproteinase 13 
Collagenase 3 (471 aa, ~54 kDa) is encoded by the human MMP13 gene. This protein plays a role in the proteolysis of the extracellular matrix.
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Mice lacking tumor necrosis factor-alpha (TNF-alpha) receptors (TNFRKO mice) do not develop an inflammatory infiltrate or matrix… (More)
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Highly Cited
2003
Highly Cited
2003
Punch biopsies of human skin were obtained 1 day after irradiation with two minimal-erythema doses (MED) from either a UVB light… (More)
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Highly Cited
2002
Highly Cited
2002
AIM To determine the cellular and molecular forms of MMP-8 (collagenase-2) and MMP-13 (collagenase-3) associated with chronic… (More)
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Highly Cited
2001
Highly Cited
2001
Adult mammary tissue has been considered "resting" with minimal morphological change. Here, we reveal the dynamic nature of the… (More)
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Highly Cited
2001
Highly Cited
2001
It has been suggested that increased collagenase-3 (MMP-13) activity plays a pivotal role in the pathogenesis of osteoarthritis… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Several recent studies attempted to classify plaques as those prone to cause clinical manifestations (vulnerable… (More)
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Highly Cited
1997
Highly Cited
1997
Human collagenase-3 (MMP13) is a recently identified member of the matrix metalloproteinase (MMP) family that is expressed in… (More)
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Highly Cited
1996
Highly Cited
1996
The cDNA of a novel matrix metalloproteinase, collagenase-3 (MMP-13) has been isolated from a breast tumor library (Freije, J. M… (More)
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Highly Cited
1996
Highly Cited
1996
Proteolysis of triple-helical collagen is an important step in the progression toward irreversible tissue damage in… (More)
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Highly Cited
1996
Highly Cited
1996
Gelatinase A and membrane-type metalloproteinase (MT1-MMP) were able to process human procollagenase-3 (Mr 60,000) to the fully… (More)
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