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Mannomustine

Known as: D-Mannitol, 1,6-bis((2-chloroethyl)amino)-1,6-dideoxy-, Mannitol Nitrogen Mustard, Mannomustine [Chemical/Ingredient] 
A nitrogen mustard derivative that cross-links with DNA, causing inhibition of DNA synthesis. It may be used to treat certain cancers, but may cause… Expand
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Antineoplastic Agents, Alkylating

Narrower (2)

DegranolMannomustine Hydrochloride
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1978
1978
PROLONGATION OF RAT CARDIAC ALLOGRAFT SURVIVAL BY DONOR PRETREATMENT: SCREENING OF ANTINEOPLASTIC DRUGS
SUMMARY We have made preliminary investigations into the effect of 33 different drugs on the survival of rat cardiac allografts… Expand
1975
1975
The effect of cytostatic hexitol derivatives on haematopoietic stem cells, the L1210 leukaemia and C22LR osteosarcoma.
Abstract In a comparative study the effect of six hexitol derivatives, mannitol mustard, dibromomannitol, dianhydromannitol… Expand
1969
1969
Effect of mannitol mustard (NSC-9698) on nuclear DNA content and birefringence of Hela and Chinese hamster cells.
1969
1969
Effect of various nucleic acid and protein synthesis inhibitors on anaphylactoid inflammation in rats.
The effects of several nucleic acid and protein synthesis inhibitors (NAPSI) on dextran anaphylactoid inflammation, and on foot… Expand
1965
1965
Some effects of 1-methyl-2-p-(isopropyl-carbamoyl)-benzyl-hydrazine and mannomustine on the metabolism of human erythrocytes in vitro.
  • E. Mortensen
  • Scandinavian journal of haematology
  • 1965
    • Corpus ID: 29277978
During incubation of erythrocytes with Natulan® and Degranol® a depression of the concentrations of reduced glutathione and… Expand
Highly Cited
1964
Highly Cited
1964
DOSE-RESPONSE RELATIONSHIPS FOR AGENTS INHIBITING THE IMMUNE RESPONSE.
Mice were injected with T.A.B. vaccine and, 2 days later, with various doses of different compounds. The relation between dose of… Expand
1963
1963
Physical Changes, Measured by Interference Microscopy, in fresh Landschütz Ascites Tumour Cells after Tragacanth and Mannitol Mustard Treatments
INTERFERENCE microscopy can be used to determine refractive indices with a high degree of accuracy in biological material such as… Expand
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Review
1962
Review
1962
The Clinical Application of Bone Marrow Grafting
Eight patients. were treated with total thoracic irradiation of 2500 to 3058 r and subsequently received intravenous infusions of… Expand
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1960
1960
Comparative clinical evaluation of two alkylating agents: mannitol mustard and cyclophosphamide (cytoxan).
An intensive search for agents of increased therapeutic benefit in the treatment of neoplastic disease has prompted the… Expand
1959
1959
Mannomustine in Treatment of Leukaemias, Polycythaemia, and Malignant Disorders
Baldwin, E. deF., Cournand, A., and Richards, D. W., jun. (1949). Medicine (Baltimore), 28, 201. Buechley, R. W., Drake, R. M… Expand
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