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Mannomustine

Known as: D-Mannitol, 1,6-bis((2-chloroethyl)amino)-1,6-dideoxy-, Mannitol Nitrogen Mustard, Mannomustine [Chemical/Ingredient] 
A nitrogen mustard derivative that cross-links with DNA, causing inhibition of DNA synthesis. It may be used to treat certain cancers, but may cause… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Antineoplastic Agents, Alkylating

Narrower (2)

DegranolMannomustine Hydrochloride
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1978
1978
PROLONGATION OF RAT CARDIAC ALLOGRAFT SURVIVAL BY DONOR PRETREATMENT: SCREENING OF ANTINEOPLASTIC DRUGS
SUMMARY We have made preliminary investigations into the effect of 33 different drugs on the survival of rat cardiac allografts… 
1975
1975
The effect of cytostatic hexitol derivatives on haematopoietic stem cells, the L1210 leukaemia and C22LR osteosarcoma.
1969
1969
Effect of various nucleic acid and protein synthesis inhibitors on anaphylactoid inflammation in rats.
1969
1969
Effect of mannitol mustard (NSC-9698) on nuclear DNA content and birefringence of Hela and Chinese hamster cells.
Highly Cited
1964
Highly Cited
1964
DOSE-RESPONSE RELATIONSHIPS FOR AGENTS INHIBITING THE IMMUNE RESPONSE.
Mice were injected with T.A.B. vaccine and, 2 days later, with various doses of different compounds. The relation between dose of… 
1963
1963
Physical Changes, Measured by Interference Microscopy, in fresh Landschütz Ascites Tumour Cells after Tragacanth and Mannitol Mustard Treatments
INTERFERENCE microscopy can be used to determine refractive indices with a high degree of accuracy in biological material such as… 
1962
1962
The Clinical Application of Bone Marrow Grafting
IT is n1ow well recognised that bone marrow depression is often the limiting factor in the chemotherapy of malignant disease and… 
Review
1962
Review
1962
The Clinical Application of Bone Marrow Grafting
Eight patients. were treated with total thoracic irradiation of 2500 to 3058 r and subsequently received intravenous infusions of… 
1960
1960
Comparative clinical evaluation of two alkylating agents: mannitol mustard and cyclophosphamide (cytoxan).
An intensive search for agents of increased therapeutic benefit in the treatment of neoplastic disease has prompted the… 
1959
1959
Mannomustine in Treatment of Leukaemias, Polycythaemia, and Malignant Disorders
Baldwin, E. deF., Cournand, A., and Richards, D. W., jun. (1949). Medicine (Baltimore), 28, 201. Buechley, R. W., Drake, R. M… 
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