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MUTYH wt Allele

Known as: MutY, E. coli, Homolog of Gene, MutY Homolog wt Allele, CYP2C 
Human MUTYH allele is located within 1p34.3-p32.1 and is approximately 92 kb in length. This allele, which encodes A/G-specific adenine DNA… 
National Institutes of Health

Related topics

Related topics

6 relations
A/G-Specific Adenine DNA GlycosylaseCell MaintenanceDNA RepairHomo sapiens

Broader (1)

MUTYH gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Understanding MYH-associated neoplasia.
I n 2002, a group of molecular geneticists from Cardiff in Wales reported a new, inherited syndrome of colorectal cancer… 
2008
2008
Genetic polymorphisms in hMTH1, hOGG1 and hMYH and risk of chronic benzene poisoning in a Chinese occupational population.
2007
2007
Mutagenesis and Repair in Bacillus anthracis: the Effect of Mutators
ABSTRACT We have generated mutator strains of Bacillus anthracis Sterne by using directed gene knockouts to investigate the… 
Highly Cited
2005
Highly Cited
2005
Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and…
2003
2003
Overexpression of hMTH in peripheral lymphocytes and risk of prostate cancer: a case‐control analysis
Oxidative damage is an important factor in prostate carcinogenesis, and overexpression of human MutT homolog (hMTH), a repair… 
2003
2003
Short Communication Proportion and Phenotype of MYH-Associated Colorectal Neoplasia in a Population-Based Series of Finnish Colorectal Cancer Patients
Recessively inherited mutations in the base excision repair gene MYH have recently been associated with predisposition to… 
2002
2002
[Potential role of human DNA-repair enzymes hMTH1, hOGG1 and hMYHalpha in the hepatocarcinogenesis].
To elucidate role of the three enzymes in hepatocarcinogenesis, hMTH1, hOGG1 and hMYH, mRNA expression were examined by using RT… 
Highly Cited
2001
Highly Cited
2001
Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria.
Human MutY homolog (hMYH), an adenine DNA glycosylase, can effectively remove misincorporated adenines opposite template G or 8… 
2001
2001
Alteration of DNA base excision repair enzymes hMYH and hOGG1 in hydrogen peroxide resistant transformed human breast cells.
BACKGROUND Oxidative stress is a major causative agent of carcinogenesis, aging, and a number of diseases. 8-oxoG is the most… 
2001
2001
Autoantibody to DNA excision repair enzyme hMYH in a patient with rheumatic disease.
We screened a human HepG2 cell cDNA expression library using serum from a patient with rheumatic disease. This serum had… 
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