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MSLN gene
Known as:
Mesothelin Gene
, MPF
, CAK1
Expand
This gene may be involved in cellular adhesion.
National Institutes of Health
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Related topics
Related topics
5 relations
Cell Adhesion
Immune response
MSLN protein, human
mesothelin
Narrower (1)
MSLN wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
The role of mesothelin in tumor progression and targeted therapy.
Zhewei Tang
,
M. Qian
,
Mitchell Ho
Anti-Cancer Agents in Medicinal Chemistry
2013
Corpus ID: 13769955
Mesothelin, a glycosylphosphatidylinositol (GPI) anchored cell surface protein, is a potential target for antibody-based cancer…
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Highly Cited
2012
Highly Cited
2012
Mesothelin, a novel immunotherapy target for triple negative breast cancer
J. Tchou
,
Liang-Chuan S. Wang
,
+8 authors
Paul J. L. Zhang
Breast Cancer Research and Treatment
2012
Corpus ID: 25496168
Mesothelin is a cell-surface glycoprotein present on mesothelial cells and elicits T cell responses in a variety of cancers…
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Highly Cited
2011
Highly Cited
2011
Co-Expression of Mesothelin and CA125 Correlates With Unfavorable Patient Outcome in Pancreatic Ductal Adenocarcinoma
T. Einama
,
H. Kamachi
,
+11 authors
S. Todo
Pancreas
2011
Corpus ID: 33409915
Objectives: Recent studies have shown that the high affinity of mesothelin-CA125 interaction might cause intracavitary tumor…
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Highly Cited
2010
Highly Cited
2010
Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes
Jennifer A. Belisle
,
S. Horibata
,
+8 authors
M. Patankar
Molecular Cancer
2010
Corpus ID: 7268779
BackgroundMUC16 is a cell surface mucin expressed at high levels by epithelial ovarian tumors. Following proteolytic cleavage…
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Highly Cited
2009
Highly Cited
2009
High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma
W. Cheng
,
C. Huang
,
+5 authors
C.-A. Chen
British Journal of Cancer
2009
Corpus ID: 18791810
The objective of this paper is to investigate the mesothelin expression level to the clinicopathological features, chemoresponse…
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Highly Cited
2009
Highly Cited
2009
Influence of Ovarian Cancer Risk Status on the Diagnostic Performance of the Serum Biomarkers Mesothelin, HE4, and CA125
C. Shah
,
K. Lowe
,
+9 authors
C. Drescher
Cancer Epidemiology, Biomarkers and Prevention
2009
Corpus ID: 11142010
Objective: To evaluate the effect of ovarian cancer risk on the performance of the serum biomarkers mesothelin, human epididymis…
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Highly Cited
2007
Highly Cited
2007
Urinary mesothelin provides greater sensitivity for early stage ovarian cancer than serum mesothelin, urinary hCG free beta subunit and urinary hCG beta core fragment.
D. Badgwell
,
Zhen Lu
,
+7 authors
R. Bast
Gynecologic Oncology
2007
Corpus ID: 19639344
Highly Cited
2007
Highly Cited
2007
Mesothelin Expression in Human Lung Cancer
Mitchell Ho
,
T. Bera
,
+4 authors
I. Pastan
Clinical Cancer Research
2007
Corpus ID: 10717251
Purpose: To investigate mesothelin as a new target for immunotherapy in lung cancer. Experimental Design: Mesothelin mRNA and…
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Highly Cited
2005
Highly Cited
2005
Expression of Mesothelin, Fascin, and Prostate Stem Cell Antigen in Primary Ovarian Mucinous Tumors and Their Utility in Differentiating Primary Ovarian Mucinous Tumors From Metastatic Pancreatic…
D. Cao
,
Hongxiu Ji
,
B. Ronnett
International Journal of Gynecological Pathology
2005
Corpus ID: 626068
Metastatic pancreatic mucinous adenocarcinomas in the ovaries can be difficult to distinguish from primary ovarian mucinous…
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Highly Cited
2005
Highly Cited
2005
Soluble mesothelin-related protein--a blood test for mesothelioma.
B. Robinson
,
J. Creaney
,
+6 authors
I. Hellstrom
Lung Cancer
2005
Corpus ID: 26236501
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