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Biological and clinical significance of haptoglobin polymorphism in humans.
TLDR
The strong genetic pressure favoring the 2-2 phenotype suggests an important role of haptoglobin in human pathology and is explained by a phenotype-dependent modulation of oxidative stress and prostaglandin synthesis.
Lowered ω3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients
TLDR
There is an abnormal metabolism of omega3 PUFAs in depression and the FA alterations in depression are related to the inflammatory response in that illness; and the disorders may persist despite successful antidepressant treatment.
Biological and clinical aspects of the vitamin D binding protein (Gc-globulin) and its polymorphism.
TLDR
DBP is a highly polymorphic serum protein with three common alleles (Gc1F, Gc1S and Gc2) and more than 120 rare variants that are a useful tool for anthropological studies to discriminate and to reveal ancestral links between populations.
Metabolite and ionic composition of follicular fluid from different-sized follicles and their relationship to serum concentrations in dairy cows.
TLDR
The results from the present study suggest that the oocyte and the granulosa cells of dairy cows grow and mature in a biochemical environment that changes from small to large follicles.
Noninvasive diagnosis of liver cirrhosis using DNA sequencer–based total serum protein glycomics
TLDR
The 'clinical glycomics' technology, based on DNA sequencer/fragment analyzers, yielded a biomarker that distinguished compensated cirrhotic from noncirrhotic chronic liver disease patients, with 79% sensitivity and 86% specificity, which could obviate biopsy in many cirrhosis patients.
Assessment of renal function in recently admitted critically ill patients with normal serum creatinine.
TLDR
In recently admitted critically ill patients with normal serum creatinine, serum creat inine had a low sensitivity for detection of renal dysfunction, and the Cockcroft-Gault formula nor the MDRD equations were specific enough for assessment of renal function.
Diagnosing and monitoring hepatocellular carcinoma with alpha-fetoprotein: new aspects and applications.
TLDR
The aim of this paper is to review the present knowledge on AFP and its related parameters in diagnosing and monitoring HCC and to suggest some of them are recommended as a complementary test but cannot replace serum AFP as the golden standard of diagnostic markers for hepatocellular carcinoma.
Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae, Gardnerella vaginalis and bacterial vaginosis
TLDR
Results obtained by combining culture and PCR-based methods to characterize the normal and disturbed vaginal microflora indicate that much is to be learned about the composition of the vaginalmicroflora and its relation to the etiology of BV.
Metabolic changes in follicular fluid of the dominant follicle in high-yielding dairy cows early post partum.
TLDR
The results from the present study confirm that the typical metabolic adaptations which can be found in serum of high-yielding dairy cows shortly post partum, are reflected in follicular fluid and, therefore, may affect the quality of both the oocyte and the granulosa cells.
Haptoglobin polymorphisms and iron homeostasis in health and in disease.
TLDR
The identification of functional differences in haptoglobin molecules resulting from relatively common polymorphisms has further elucidated the importance of Hptoglobin in iron homeostasis and in disease processes influenced by iron metabolism.
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