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MS-551

Known as: MS 551 
 
National Institutes of Health

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nifekalant

Papers overview

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1998
1998
Electrophysiological effects of MS-551, a new class III agent: comparison with dl-sotalol in dogs.
MS-551 is a newly synthesized, nonspecific K+ channel blocker. To elucidate its electrophysiological and potential proarrhythmic… Expand
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1996
1996
Differential effects of MS-551 and E-4031 on action potentials and the delayed rectifier K+ current in rabbit ventricular myocytes.
OBJECTIVE The frequency-dependent effects of MS-551 on the action potential duration (APD) and the underlying ionic mechanisms… Expand
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1995
1995
A new class III antiarrhythmic drug, MS-551, blocks the inward rectifier potassium channel in isolated guinea pig ventricular myocytes.
We have studied the effects of MS-551 on the inward rectifier potassium channel (IK1) in isolated guinea-pig ventricular myocytes… Expand
1995
1995
Electrophysiological Effects of MS‐551 in Humans: A Class III Antiarrhythmic Agent
To investigate the clinical effects of MS‐551, a Class III antiarrhythmic agent, 11 patients underwent electrophysiological study… Expand
1995
1995
MS‐551 Protects Against Ventricular Fibrillation in a Chronic Canine Model of Sudden Cardiac Death
Summary We studied the electrophysiologic and anti-fibrillatory properties of MS-551 (l,3-dimethyl-6-{(2-[N-hydroxy-ethyl)-3-(4… Expand
1995
1995
Effects of the new class III antiarrhythmic drug MS-551 and d-sotalol on canine coronary ligation-reperfusion ventricular arrhythmias.
The antiarrhythmic effects of a new class III antiarrhythmic agent, MS-551 [1,3-dimethyl-6-(2-[N-(2-hydroxyethyl)-3-(4… Expand
1995
1995
Inhibition of ATP-sensitive potassium channels in cardiac myocytes by the novel class III antiarrhythmic agent MS-551.
The novel class III antiarrhythmic agent, MS-551, has recently been shown to attenuate the decrease in ventricular effective… Expand
1994
1994
Effects of MS-551, a New Class III Antiarrhythmic Drug, on Programmed Stimulation-Induced Ventricular Arrhythmias, Electrophysiology, and Hemodynamics in a Canine Myocardial Infarction Model
Summary: We examined the effects of MS-551 (1,3-dimethyl-6-{(2-[N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino]ethylamino} 2,4… Expand
Highly Cited
1993
Highly Cited
1993
Effects of MS‐551, a new class III antiarrhythmic drug, on action potential and membrane currents in rabbit ventricular myocytes
1 Electrophysiological effects of MS‐551, a new class III antiarrhythmic drug, were examined and compared with those of… Expand
Highly Cited
1992
Highly Cited
1992
Antiarrhythmic effects of MS-551, a new class III antiarrhythmic agent, on canine models of ventricular arrhythmia.
The antiarrhythmic effects of MS-551, which prolongs cardiac action potential duration without affecting the maximum upstroke… Expand
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