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MS-551

Known as: MS 551 
National Institutes of Health

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nifekalant

Papers overview

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2002
2002
Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related…
KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] is a newly… 
2001
2001
Initial experience with nifekalant hydrochloride (MS-551), a novel class III antiarrhythmic agent, in patients with acute extensive infarction and severe ventricular dysfunction.
Nifekalant hydrocholoride, a novel class III antiarrhythmic agent, was used as the treatment in 4 patients with extensive… 
2001
2001
Efficacy of nifekalant hydrochloride on the treatment of life-threatening ventricular tachyarrhythmias during reperfusion for acute myocardial infarction
2000
2000
QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide.
1998
1998
MS‐551 and KCB‐328, two class III drugs aggravated adrenaline‐induced arrhythmias
We investigated the proarrhythmic effects of MS‐551 and KCB‐328, class III antiarrhythmic drugs using adrenaline‐induced… 
1998
1998
Electrophysiologic effects of intravenous MS-551, a novel class III antiarrhythmic agent, on human atrium and ventricle.
The effects of intravenous MS-551, a new class III antiarrhythmic drug, on atrium and ventricle were evaluated in 6 patients with… 
1996
1996
Effects of dofetilide, a class III antiarrhythmic drug, on various ventricular arrhythmias in dogs.
Dofetilide, a new class III antiarrhythmic agent, was tested in various kinds of canine ventricular arrhythmias to compare its… 
1995
1995
MS‐551 Protects Against Ventricular Fibrillation in a Chronic Canine Model of Sudden Cardiac Death
Summary We studied the electrophysiologic and anti-fibrillatory properties of MS-551 (l,3-dimethyl-6-{(2-[N-hydroxy-ethyl)-3-(4… 
Highly Cited
1995
Highly Cited
1995
Anticholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells. Different molecular mechanisms.
BACKGROUND It is well known that vagal stimulation increases the vulnerability to atrial fibrillation via muscarinic receptor… 
1994
1994
Antiarrhythmic Agent, MS‐551, Protects Against Pinacidil + Hypoxia‐Induced Ventricular Fibrillation in Langendorff‐Perfused Rabbit Isolated Heart
Summary We studied the electrophysiologic and anti-fibrillatory effects of the class III agent MS-551 in a rabbit isolated heart… 
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