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MS-551

Known as: MS 551 
 
National Institutes of Health

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nifekalant

Papers overview

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2001
2001
Initial experience with nifekalant hydrochloride (MS-551), a novel class III antiarrhythmic agent, in patients with acute extensive infarction and severe ventricular dysfunction.
Nifekalant hydrocholoride, a novel class III antiarrhythmic agent, was used as the treatment in 4 patients with extensive… Expand
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1998
1998
Electrophysiological effects of MS-551, a new class III agent: comparison with dl-sotalol in dogs.
MS-551 is a newly synthesized, nonspecific K+ channel blocker. To elucidate its electrophysiological and potential proarrhythmic… Expand
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1998
1998
MS-551 and KCB-328, two class III drugs aggravated adrenaline-induced arrhythmias.
We investigated the proarrhythmic effects of MS-551 and KCB-328, class III antiarrhythmic drugs using adrenaline-induced… Expand
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1995
1995
Inhibition of ATP-sensitive potassium channels in cardiac myocytes by the novel class III antiarrhythmic agent MS-551.
The novel class III antiarrhythmic agent, MS-551, has recently been shown to attenuate the decrease in ventricular effective… Expand
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1995
1995
Effects of the new class III antiarrhythmic drug MS-551 and d-sotalol on canine coronary ligation-reperfusion ventricular arrhythmias.
The antiarrhythmic effects of a new class III antiarrhythmic agent, MS-551 [1,3-dimethyl-6-(2-[N-(2-hydroxyethyl)-3-(4… Expand
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1995
1995
A new class III antiarrhythmic drug, MS-551, blocks the inward rectifier potassium channel in isolated guinea pig ventricular myocytes.
We have studied the effects of MS-551 on the inward rectifier potassium channel (IK1) in isolated guinea-pig ventricular myocytes… Expand
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1995
1995
MS-551 protects against ventricular fibrillation in a chronic canine model of sudden cardiac death.
We studied the electrophysiologic and antifibrillatory properties of MS-551 (1,3-dimethyl-6-((2-[N-hydroxy-ethyl)-3-(4… Expand
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1994
1994
Effects of MS-551, a new class III antiarrhythmic drug, on programmed stimulation-induced ventricular arrhythmias, electrophysiology, and hemodynamics in a canine myocardial infarction model.
We examined the effects of MS-551 (1,3-dimethyl-6-[(2-[N-(2-hydroxyethyl)-3-(4- nitrophenyl)propylamino]ethylamino] 2,4(1H,3H… Expand
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1993
1993
Effects of MS-551, a new class III antiarrhythmic drug, on action potential and membrane currents in rabbit ventricular myocytes.
1. Electrophysiological effects of MS-551, a new class III antiarrhythmic drug, were examined and compared with those of… Expand
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1992
1992
Antiarrhythmic effects of MS-551, a new class III antiarrhythmic agent, on canine models of ventricular arrhythmia.
The antiarrhythmic effects of MS-551, which prolongs cardiac action potential duration without affecting the maximum upstroke… Expand
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