nifekalant
National Institutes of Health
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Background: In Japan, intravenous nifekalant (NIF) was often used for direct current cardioversion-resistant ventricular…
BACKGROUND
Intravenous amiodarone (AMD) has been used for the treatment of ventricular tachycardia/fibrillation (VT/VF) in…
The chronic atrioventricular block dog is a useful model for predicting the future onset of drug-induced long QT syndrome in…
Class III antiarrhythmic agents have been widely used to suppress ventricular tachyarrhythmias in patients with heart failure…
BACKGROUND
Spiral re-entry plays the principal role in the genesis of ventricular tachycardia and ventricular fibrillation (VT/VF…
Nifekalant (NF), a pure K+ channel blocker developed in Japan, has been reported to be effective in the treatment of life…
Nifekalant, a class III antiarrhythmic drug, has been shown to suppress ventricular tachyarrhythmias, but its effects on AF are…
Pure class III antiarrhythmic agents cause reverse use-dependent QT prolongation. Nifekalant is a new class III antiarrhythmic…
INTRODUCTION Most sudden cardiac death is primarily the result of lethal ventricular arrhythmias. The Cardiac Arrhythmia…