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MPO gene

Known as: MPO, MYELOPEROXIDASE, Myeloperoxidase Gene 
This gene is involved in the modulation of neutrophil microbicidal activity.
National Institutes of Health

Related topics

Related topics

6 relations
Antimicrobial EffectMyeloperoxidase MeasurementOxidation-ReductionPeroxidase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Hypochlorous acid via peroxynitrite activates protein kinase Cθ and insulin resistance in adipocytes
We recently reported that genetic deletion of myeloperoxidase (MPO) alleviates obesity-related insulin resistance in mice in vivo… 
2012
2012
Preservation of biological function despite oxidative modification of the apolipoprotein A-I mimetic peptide 4F
Myeloperoxidase (MPO)-derived hypochlorous acid induces changes in HDL function via redox modifications at the level of… 
Highly Cited
2007
Highly Cited
2007
Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR−/− Mice
Objective—Atherosclerosis is a chronic inflammatory disease in which the immune system plays an important role. Neutrophils have… 
Highly Cited
2006
Highly Cited
2006
A testing framework for identifying susceptibility genes in the presence of epistasis.
An efficient testing strategy called the "focused interaction testing framework" (FITF) was developed to identify susceptibility… 
2004
2004
No association of G-463A myeloperoxidase gene polymorphism with MPO-ANCA-associated vasculitis.
BACKGROUND The activation of neutrophils and monocytes by ANCA, resulting in the release of reactive oxygen species and proteases… 
2003
2003
Myeloperoxidase G-463A polymorphism and Alzheimer's disease in the ApoEurope study
2001
2001
Possible risk reduction in esophageal cancer associated with MPO -463 A allele.
Myeloperoxidase (MPO), an enzyme found in lysosomes of phagocytes, causes hydroxy radicals linked to DNA damage and activation of… 
Highly Cited
2001
Highly Cited
2001
Association between Alzheimer's Disease and a Functional Polymorphism in the Myeloperoxidase Gene
A polymorphism in the Myeloperoxidase gene (MPO) has previously been demonstrated to be associated with gender-specific risk in… 
1998
1998
Cloning and characterization of a cDNA encoding a novel heterogeneous nuclear ribonucleoprotein-like protein and its expression in myeloid leukemia cells.
We isolated a cDNA encoding a novel heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein on DNA affinity screening of a… 
1989
1989
Assignment of the human myeloperoxidase gene (MPO) to bands q21.3----q23 of chromosome 17.
Using a human myeloperoxidase cDNA, we have mapped the human myeloperoxidase gene to chromosome 17 at q21.3----q23 by in situ… 
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