Skip to search formSkip to main contentSkip to account menu

MPG wt Allele

Known as: anpg, AAG, N-Methylpurine-DNA Glycosylase wt Allele 
Human MPG wild-type allele is located in the vicinity of 16p13.3 and is approximately 9 kb in length. This allele, which encodes DNA-3-methyladenine… 
National Institutes of Health

Related topics

Related topics

6 relations
16p13.3DNA RepairDepurinationHomo sapiens

Broader (1)

MPG gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
X‐linked Opitz syndrome: Novel mutations in the MID1 gene and redefinition of the clinical spectrum
Opitz (or G/BBB) syndrome is a pleiotropic genetic disorder characterized by hypertelorism, hypospadias, and additional midline… 
Highly Cited
2000
Highly Cited
2000
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG.
The human 3-methyladenine DNA glycosylase [alkyladenine DNA glycosylase (AAG)] catalyzes the first step of base excision repair… 
Highly Cited
1999
Highly Cited
1999
Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity
Activation of the p53 tumor suppressor protein can lead to either cell cycle arrest or apoptosis. Several functional domains… 
Highly Cited
1999
Highly Cited
1999
The Opitz syndrome gene product, MID1, associates with microtubules.
Opitz syndrome (OS) is a genetically heterogeneous disorder characterized by defects of the ventral midline, including… 
Highly Cited
1995
Highly Cited
1995
Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA.
The human carcinogen vinyl chloride is metabolized in the liver to reactive intermediates which generate various ethenobases in… 
Highly Cited
1994
Highly Cited
1994
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases.
The deamination of adenine residues in DNA generates hypoxanthine, which is mutagenic since it gives rise to an A.T to G.C… 
Highly Cited
1990
Highly Cited
1990
Binding of d‐methadone, 1‐methadone, and dl‐methadone to proteins in plasma of healthy volunteers: Role of the variants of α1‐acid glycoprotein
The plasma concentrations of α1‐acid glycoprotein (AAG), albumin, triglycerides, cholesterol, and total proteins, as well as the… 
Highly Cited
1989
Highly Cited
1989
Effects of deletions in the N-terminal basic arm of brome mosaic virus coat protein on RNA packaging and systemic infection
The first 25 amino acids of brome mosaic virus (BMV) coat protein include 8 basic and no acidic residues and are implicated in… 
Highly Cited
1980
Highly Cited
1980
Lidocaine plasma protein binding
The percent of unbound lidocaine in the plasma of 24 healthy subjects was measured by equilibrium dialysis after addition of 3 µg… 
Highly Cited
1977
Highly Cited
1977
Interactions of alpha1-acid glycoprotein with the immune system. I. Purification and effects upon lymphocyte responsiveness.
Alpha1-acid glycoprotein (AAG) is a constituent of normal serum which is elevated in concentration in the acute phase of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)