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Depurination

Depurination involves cleavage of the N-glycosidic link between a purine base and the remaining deoxyribose portion of the effected nucleotide in DNA… 
National Institutes of Health

Related topics

Related topics

3 relations
3-methyladenine-DNA glycosylaseMPG geneMPG wt Allele

Papers overview

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Highly Cited
2002
Highly Cited
2002
Theoretical study on the stability of N-glycosyl bonds: why does N7-platination not promote depurination?
The depurination reaction of guanosine, protonated or modified with cisplatin at the N7 position, has been studied by density… 
Highly Cited
1999
Highly Cited
1999
Stannous chloride mediates single strand breaks in plasmid DNA through reactive oxygen species formation.
Highly Cited
1991
Highly Cited
1991
Ribosomal RNA identity elements for ricin A-chain recognition and catalysis.
Review
1990
Review
1990
Errors in DNA synthesis: a source of spontaneous mutations.
Highly Cited
1983
Highly Cited
1983
Dialkylformamidines: depurination resistant N6-protecting group for deoxyadenosine.
Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6… 
Highly Cited
1982
Highly Cited
1982
Role of depurination in mutagenesis by chemical carcinogens.
The effect of modifying phi chi 174 viral DNA by the chemical carcinogens beta-propiolactone, N-acetoxyacetylaminofluorene and… 
Highly Cited
1974
Highly Cited
1974
Direct determination of DNA nucleotide sequences: structure of a fragment of bacteriophage phiX172 DNA.
Highly Cited
1970
Highly Cited
1970
The intermediate in the degradation of DNA alkylated with a monofunctional alkylating agent.
Highly Cited
1969
Highly Cited
1969
The letal action of monofunctional and bifunctional alkylating agents on T7 coliphage.
1967
1967
The interaction of oligodeoxynucleotides with denatured DNA.
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