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Depurination

Depurination involves cleavage of the N-glycosidic link between a purine base and the remaining deoxyribose portion of the effected nucleotide in DNA… Expand
National Institutes of Health

Papers overview

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2014
2014
Depurination has attracted considerable attention since a long time for it is closely related to the damage and repair of nucleic… Expand
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Highly Cited
2012
Highly Cited
2012
Claims of extreme survival of DNA have emphasized the need for reliable models of DNA degradation through time. By analysing… Expand
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Highly Cited
2010
Highly Cited
2010
We have achieved the ability to synthesize thousands of unique, long oligonucleotides (150mers) in fmol amounts using parallel… Expand
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Highly Cited
2007
Highly Cited
2007
High-throughput direct sequencing techniques have recently opened the possibility to sequence genomes from Pleistocene organisms… Expand
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Highly Cited
2000
Highly Cited
2000
Apurinic/apyrimidinic (AP) sites are common DNA lesions that arise from spontaneous depurination or by base excision repair (BER… Expand
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Highly Cited
1998
Highly Cited
1998
One of the most prevalent lesions in DNA is the apurinic/apyrimidinic (AP) site, which is derived from the cleavage of the N… Expand
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Highly Cited
1995
Highly Cited
1995
Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide in inflamed tissues. We have demonstrated… Expand
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Highly Cited
1991
Highly Cited
1991
A cDNA clone encoding a neural-specific putative protein-tyrosine-phosphatase (protein-tyrosine-phosphate phosphohydrolase, EC 3… Expand
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Highly Cited
1979
Highly Cited
1979
We describe a technique for transferring electrophoretically separated bands of double-stranded DNA from agarose gels to… Expand
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Highly Cited
1972
Highly Cited
1972
 
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