Depurination

Depurination involves cleavage of the N-glycosidic link between a purine base and the remaining deoxyribose portion of the effected nucleotide in DNA… (More)

Topic mentions per year

Topic mentions per year

1962-2017
010203019622017

Papers overview

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Highly Cited
2010
Highly Cited
2010
We have achieved the ability to synthesize thousands of unique, long oligonucleotides (150mers) in fmol amounts using parallel… (More)
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Highly Cited
2007
Highly Cited
2007
High-throughput direct sequencing techniques have recently opened the possibility to sequence genomes from Pleistocene organisms… (More)
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Highly Cited
2001
Highly Cited
2001
Treatment of SENCAR mouse skin with dibenzo[a,l]pyrene results in abundant formation of abasic sites that undergo error-prone… (More)
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1999
1999
DNA fragments that show a pattern of differential expression on differential display gels must be eluted from the gel matrix and… (More)
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Highly Cited
1998
Highly Cited
1998
One of the most prevalent lesions in DNA is the apurinic/apyrimidinic (AP) site, which is derived from the cleavage of the N… (More)
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1994
1994
Products formed from defined oligodeoxyribonucleotide tetramers (oligonucleotides) by depurination at pH 5.0 and 90 degrees C… (More)
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1984
1984
The mutagenic consequences of damage to DNA produced by low pH and high temperature have been determined in a forward mutational… (More)
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1981
1981
Introduction of apurinic sites into phi X174 am3 DNA leads to loss of biological activity when measured in a transfection assay… (More)
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Highly Cited
1979
Highly Cited
1979
We describe a technique for transferring electrophoretically separated bands of double-stranded DNA from agarose gels to… (More)
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Highly Cited
1972
Highly Cited
1972
 
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