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3-methyladenine-DNA glycosylase

Known as: alkyladenine DNA glycosylase, 3-MeAde-DNA glycosylase, N-Methylpurine-DNA Glycosylase 
DNA-3-methyladenine glycosylase (298 aa, ~33 kDa) is encoded by the human MPG gene. This protein plays a role in the excision of alkylated bases from… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell NucleusDNA RepairDNA repair proteinDNA-3-methyladenine glycosidase II

Broader (1)

DNA glycosylase

Papers overview

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Highly Cited
2010
Highly Cited
2010
Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.
Highly Cited
2009
Highly Cited
2009
Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).
The human 3-methyladenine DNA glycosylase (AAG) recognizes and excises a broad range of purines damaged by alkylation and… 
2007
2007
Altering DNA base excision repair: Use of nuclear and mitochondrial‐targeted N‐methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents
Primary astrocyte cultures were used to investigate the modulation of DNA repair as a tool for sensitizing astrocytes to… 
2004
2004
Cloning of Escherichia coli genes encoding 3-methyladenine DNA glycosylases I and II
SummaryWe have constructed two recombinant plasmids which harbour functions involved in DNA repair of alkylation damage in… 
2000
2000
Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase.
The human 3-methyladenine DNA glycosylase (AAG) is a repair enzyme that removes a number of damaged bases from DNA, including… 
Highly Cited
1994
Highly Cited
1994
1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase).
A lethal DNA adduct induced by methylating agents, 3-methyladenine (m3A), is removed by both the constitutive (Tag) and inducible… 
Highly Cited
1992
Highly Cited
1992
Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine.
We previously described a protein, isolated from human tissues and cells, that bound to a defined double-stranded oligonucleotide… 
1991
1991
Induction of S.cerevisiae MAG 3-methyladenine DNA glycosylase transcript levels in response to DNA damage.
We previously showed that the expression of the Saccharomyces cerevisiae MAG 3-methyladenine (3MeA) DNA glycosylase gene, like… 
Highly Cited
1991
Highly Cited
1991
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase.
1982
1982
Partial purification and characterization of 3-methyladenine-DNA glycosylase from human placenta.
A DNA glycosylase was isolated and purified over 1000-fold from human placentas by means of diethylamino-ethylcellulose and… 
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