DNA glycosylase

Known as: Glycosylase, DNA, DNA N glycosidase, DNA N-glycosidase 
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
02040608019772017

Papers overview

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Highly Cited
2007
Highly Cited
2007
The Arabidopsis DNA glycosylase/lyase ROS1 participates in active DNA demethylation by a base-excision pathway. ROS1 has been… (More)
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Highly Cited
2006
Highly Cited
2006
DNA methylation is a stable epigenetic mark for transcriptional gene silencing in diverse organisms including plants and many… (More)
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Highly Cited
2002
Highly Cited
2002
A functional immune system depends on the production of a wide range of immunoglobulin molecules. Immunoglobulin variable region… (More)
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Highly Cited
2002
Highly Cited
2002
Prokaryotes and lower eukaryotes possess redundant activities that remove the plethora of oxidative DNA base damages produced… (More)
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Highly Cited
2001
Highly Cited
2001
Mitochondria are not only the major site for generation of reactive oxygen species, but also one of the main targets of oxidative… (More)
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Highly Cited
2000
Highly Cited
2000
Gene-targeted knockout mice have been generated lacking the major uracil-DNA glycosylase, UNG. In contrast to ung- mutants of… (More)
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Highly Cited
1998
Highly Cited
1998
Three high-resolution crystal structures of DNA complexes with wild-type and mutant human uracil-DNA glycosylase (UDG), coupled… (More)
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Highly Cited
1997
Highly Cited
1997
Oxidative DNA damage is generated by reactive oxygen species. The mutagenic base, 8-oxoguanine, formed by this process, is… (More)
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Highly Cited
1996
Highly Cited
1996
ANY uracil bases in DNA, a result of either misincorporation or deamination of cytosine, are removed by uracil-DNA glycosylase… (More)
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Highly Cited
1991
Highly Cited
1991
Substrate specificities of FPG protein (also known as formamidopyrimidine DNA glycosylase) and 8-hydroxyguanine endonuclease were… (More)
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