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MK-886

Known as: MK 886, MK886 cpd 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

IndolesLipoxygenase Inhibitors
L 663536

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Sleep and neurochemical modulation by the nuclear peroxisome proliferator-activated receptor α (PPAR-α) in rat
2016
2016
Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study.
2010
2010
Microsomal prostaglandin E synthase‐1 and cyclooxygenase‐2 are both required for ischaemic excitotoxicity
Background and purpose:  Although both microsomal prostaglandin E synthase (mPGES)‐1 and cyclooxygenase (COX)‐2 are critical… 
1999
1999
Inhibition by Leukotriene Inhibitors, and Calcium and Platelet‐activating Factor Antagonists, of Acute Gastric and Intestinal Damage in Arthritic Rats and in Cholinomimetic‐treated Mice
  • K. Rainsford
  • The Journal of pharmacy and pharmacology
  • 1999
  • Corpus ID: 22591684
The leukotrienes, platelet activating factor and intracellular calcium have been implicated in the development of gastro… 
Highly Cited
1998
Highly Cited
1998
Inhibitors of lipoxygenase metabolism exert synergistic effects with retinoic acid on differentiation of human leukemia HL-60 cells.
1994
1994
The 5-lipoxygenase inhibitors ZD2138 and ZM230487 are potent and selective inhibitors of several antigen-induced guinea-pig pulmonary responses.
1993
1993
Photoaffinity labeling of the leukotriene D4 receptor in guinea pig lung.
Highly Cited
1991
Highly Cited
1991
ATP‐dependent leukotriene export from mastocytoma cells
Highly Cited
1991
Highly Cited
1991
Role of leukotriene C4 in mucosal damage caused by necrotizing agents and indomethacin in the rat stomach.
1991
1991
Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors.
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