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MK-886

Known as: MK 886, MK886 cpd 
 
National Institutes of Health

Papers overview

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2009
2009
BACKGROUND Hepatic ischemia-reperfusion injury (I/R) may occur in transplantation, trauma, and elective hepatic resections… Expand
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Review
2008
Review
2008
Leukotrienes have physiological roles in innate immune responses and pathological roles in inflammatory diseases, such as asthma… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Recent reports point to an important role of leukotrienes in atherogenesis. Leukotrienes are produced by 5… Expand
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2005
2005
A series of potent and selective inhibitors of the inducible microsomal PGE2 synthase (mPGES-1) has been developed based on the… Expand
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Highly Cited
2001
Highly Cited
2001
Exocrine ductal carcinoma of the pancreas has been associated with smoking, and the tobacco-specific nitrosamine 4… Expand
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Highly Cited
1999
Highly Cited
1999
Lung cancer is the leading cause of death in the United States, and it demonstrates a strong etiological association with smoking… Expand
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Highly Cited
1997
Highly Cited
1997
Frankincense extracts and boswellic acids, biologically active pentacyclic triterpenes of frankincense, block leukotriene… Expand
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1993
1993
To elucidate the role of leukotrienes (LT) in allergic asthma in humans the effect of MK-886, an LT biosynthesis inhibitor, was… Expand
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Highly Cited
1990
Highly Cited
1990
LEUKOTRIENES, the biologically active metabolites of arachidonic acid, have been implicated in a variety of inflammatory… Expand
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Highly Cited
1989
Highly Cited
1989
L-663,536 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2, 2-dimethylpropanoic acid) is a potent inhibitor of… Expand
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