MK-886

Known as: MK 886, MK886 cpd 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
010203019892017

Papers overview

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2009
2009
BACKGROUND Hepatic ischemia-reperfusion injury (I/R) may occur in transplantation, trauma, and elective hepatic resections… (More)
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2007
Highly Cited
2007
This study evaluates the potential for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) to activate peroxisome… (More)
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2006
2006
BACKGROUND Recent reports point to an important role of leukotrienes in atherogenesis. Leukotrienes are produced by 5… (More)
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2005
2005
A series of potent and selective inhibitors of the inducible microsomal PGE2 synthase (mPGES-1) has been developed based on the… (More)
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2000
Highly Cited
2000
Thrombosis and inflammation involve complex platelet-leukocyte interaction, the details of which are not fully elucidated… (More)
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Highly Cited
1999
Highly Cited
1999
Lung cancer is the leading cause of death in the United States, and it demonstrates a strong etiological association with smoking… (More)
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1993
1993
To elucidate the role of leukotrienes (LT) in allergic asthma in humans the effect of MK-886, an LT biosynthesis inhibitor, was… (More)
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Highly Cited
1990
Highly Cited
1990
LEUKOTRIENES, the biologically active metabolites of arachidonic acid, have been implicated in a variety of inflammatory… (More)
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Highly Cited
1990
Highly Cited
1990
Leukotrienes (LTs) have been implicated as mediators of the inflammation and ulceration associated with ulcerative colitis and… (More)
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Highly Cited
1989
Highly Cited
1989
L-663,536 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2, 2-dimethylpropanoic acid) is a potent inhibitor of… (More)
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