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L 663536

Known as: L-663,536 
 
National Institutes of Health

Papers overview

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2000
2000
  • B. Sherman, R. Chole
  • Otolaryngology--head and neck surgery : official…
  • 2000
  • Corpus ID: 7796932
Abnormal bone remodeling is associated with important otolaryngologic diseases. In such diseases, the mechanisms of osteoclastic… Expand
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  • table 1
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Highly Cited
1998
Highly Cited
1998
Mixed acetylboswellic acids, pentacyclic triterpenes extracted from the gum resin of Boswellia serrata Roxb., significantly… Expand
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1998
1998
We investigated the contribution of eicosanoids, platelet-activating factor, tumor necrosis factor and nitric oxide to the… Expand
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1993
1993
1 A study has been made of the modulation of high‐voltage activated transient and sustained calcium currents in cultured neurones… Expand
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Highly Cited
1992
Highly Cited
1992
Erythrocyte velocity, vessel diameter, leukocyte rolling velocity, and number of adherent and emigrated leukocytes were measured… Expand
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Review
1992
Review
1992
  • D. Batt
  • Progress in medicinal chemistry
  • 1992
  • Corpus ID: 38851238
A wide variety of agents have been reported as 5-LO inhibitors. The majority of the series appear to be lipophilic reducing… Expand
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1992
1992
In the present study we investigated the involvement of lipid mediators in an experimental model of immune-complex alveolitis… Expand
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Highly Cited
1990
Highly Cited
1990
1 Platelet activating factor (PAF; 1.0 and 5.0 μg kg−1) injected in the tail vein of unanaesthetized rats dose‐dependently… Expand
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1990
1990
1 We have investigated the inhibitory activity of compound MK‐886 (formerly L‐663,536), an indole derivative, on 5‐lipoxygenase… Expand
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Highly Cited
1989
Highly Cited
1989
L-663,536 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2, 2-dimethylpropanoic acid) is a potent inhibitor of… Expand
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