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MDL 72222

Known as: MDL-72222 
National Institutes of Health

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Papers overview

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Highly Cited
2003
Highly Cited
2003
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord
Highly Cited
2003
Highly Cited
2003
Spinal 5-HT2 and 5-HT3 receptors mediate low, but not high, frequency TENS-induced antihyperalgesia in rats
Highly Cited
2001
Highly Cited
2001
Effects of 5-HT2 and 5-HT3 receptors on the modulation of nociceptive transmission in rat spinal cord according to the formalin test.
Highly Cited
1997
Highly Cited
1997
Risk Assessment Behaviour: Evaluation of Utility in the Study of 5-HT-Related Drugs in the Rat Elevated Plus-Maze Test
Highly Cited
1991
Highly Cited
1991
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat
Highly Cited
1991
Highly Cited
1991
MDL 72222, a selective 5-HT3 receptor antagonist, suppresses voluntary ethanol consumption in alcohol-preferring rats.
The effect of the selective 5-HT3 receptor antagonist MDL 72222 on voluntary ethanol consumption was examined in Sardinian… 
Highly Cited
1991
Highly Cited
1991
Evidence that spinal 5-HT1, 5-HT2 and 5-HT3 receptor subtypes modulate responses to noxious colorectal distension in the rat
Highly Cited
1990
Highly Cited
1990
5-HT3 receptors modulate spinal nociceptive reflexes
Highly Cited
1987
Highly Cited
1987
Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding
Functional serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into three subtypes: 5-HT1,-like, 5-HT2 and 5-HT3… 
Highly Cited
1984
Highly Cited
1984
MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors
SummaryThe properties of MDL 72222 (1αH,3α,5αH-tropan-3-yl-3,5-dichlorobenzoate), a novel compound with potent and selective… 
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