MCM4 protein, human

Known as: CDC21, CDC54, Cell Devision Cycle 21 Homolog 
DNA replication licensing factor MCM4 (863 aa, ~97 kDa) is encoded by the human MCM4 gene. This protein is involved in the initiation of DNA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
An interesting variant of familial glucocorticoid deficiency (FGD), an autosomal recessive form of adrenal failure, exists in a… (More)
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Highly Cited
2012
Highly Cited
2012
Natural killer (NK) cells are circulating cytotoxic lymphocytes that exert potent and nonredundant antiviral activity and… (More)
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Highly Cited
2010
Highly Cited
2010
Eukaryotic DNA replication uses kinase regulatory pathways to facilitate coordination with other processes during cell division… (More)
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Highly Cited
2007
Highly Cited
2007
Mcm4 (minichromosome maintenance–deficient 4 homolog) encodes a subunit of the MCM2-7 complex (also known as MCM2–MCM7), the… (More)
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Highly Cited
2006
Highly Cited
2006
Cdc7 kinase, conserved from yeasts to human, plays important roles in DNA replication. However, the mechanisms by which it… (More)
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Highly Cited
2005
Highly Cited
2005
Antifungal agents exert their activity through a variety of mechanisms, some of which are poorly understood. We examined changes… (More)
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2002
2002
Mcm, which is composed of six structurally related subunits (Mcm2-7), is essential for eukaryotic DNA replication. A subassembly… (More)
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Highly Cited
1999
Highly Cited
1999
Previous studies have identified an ATP-dependent DNA helicase activity intrinsic to the human minichromosome maintenance (MCM… (More)
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Highly Cited
1997
Highly Cited
1997
All six minichromosome maintenance (MCM) proteins have DNA-dependent ATPase motifs in the central domain which is conserved from… (More)
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1996
1996
In eukaryotes, tight regulatory mechanisms ensure the ordered progression through the cell cycle phases. The mechanisms that… (More)
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