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MCM4 protein, human

Known as: CDC21, CDC54, Cell Devision Cycle 21 Homolog 
DNA replication licensing factor MCM4 (863 aa, ~97 kDa) is encoded by the human MCM4 gene. This protein is involved in the initiation of DNA… 
National Institutes of Health

Related topics

Related topics

23 relations
ATP HydrolysisAdenosine TriphosphatasesCell CycleCell Cycle Control

Broader (1)

Minichromosome Maintenance Complex Component 4

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Comparative analysis of pre‐replication complex proteins in transformed and normal cells
This study examines the abundance of the major protein constituents of the pre‐replication complex (pre‐RC), both genome‐wide and… 
2010
2010
Increase of Mcm3 and Mcm4 expression in cervical squamous cell carcinomas.
PURPOSE To examine the relevance of expression of two proteins essential for DNA replication initiation, Mcm3 and Mcm4, in… 
Highly Cited
2006
Highly Cited
2006
Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-MCM6-MCM7 Complex during Epstein-Barr Virus Productive Replication
ABSTRACT Induction of Epstein-Barr virus (EBV) lytic replication blocks chromosomal DNA replication notwithstanding an S-phase… 
2004
2004
A hypophosphorylated form of RPA34 is a specific component of pre-replication centers
Replication protein A (RPA) is a three subunit single-stranded DNA-binding protein required for DNA replication. In Xenopus, RPA… 
2002
2002
Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.
The six conserved MCM proteins are essential for normal DNA replication. They share a central core of homology that contains… 
Highly Cited
2001
Highly Cited
2001
Phosphorylation of Mcm4 at Specific Sites by Cyclin-dependent Kinase Leads to Loss of Mcm4,6,7 Helicase Activity*
Mcm proteins that play an essential role in eukaryotic DNA replication are phosphorylated in vivo, and cyclin-dependent protein… 
1995
1995
Isolation and mapping of a human gene (MCM2) encoding a product homologous to yeast proteins involved in DNA replication.
From a human fetal-lung cDNA library, we isolated a gene, human MCM2, whose nucleotide sequence predicts a protein product… 
Highly Cited
1991
Highly Cited
1991
Identification and purification of a factor that binds to the Mlu I cell cycle box of yeast DNA replication genes.
In Saccharomyces cerevisiae, the genes encoding at least 10 enzymes involved in DNA replication are periodically expressed in the… 
Highly Cited
1987
Highly Cited
1987
The CDC8 transcript is cell cycle regulated in yeast and is expressed coordinately with CDC9 and CDC21 at a point preceding histone transcription.
Highly Cited
1978
Highly Cited
1978
Meiotic effects of DNA-defective cell division cycle mutations of Saccharomyces cerevisiae
The meiotic effects of several cell division cycle (cdc) mutations of Saccharomyces cerevisiae have been investigated by electron… 
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