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MCM4 protein, human

Known as: CDC21, CDC54, Cell Devision Cycle 21 Homolog 
DNA replication licensing factor MCM4 (863 aa, ~97 kDa) is encoded by the human MCM4 gene. This protein is involved in the initiation of DNA… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Initiation of eukaryotic DNA replication requires phosphorylation of the MCM complex by Dbf4-dependent kinase (DDK), composed of… Expand
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Highly Cited
2012
Highly Cited
2012
An interesting variant of familial glucocorticoid deficiency (FGD), an autosomal recessive form of adrenal failure, exists in a… Expand
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Highly Cited
2012
Highly Cited
2012
Natural killer (NK) cells are circulating cytotoxic lymphocytes that exert potent and nonredundant antiviral activity and… Expand
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Highly Cited
2010
Highly Cited
2010
Eukaryotic DNA replication uses kinase regulatory pathways to facilitate coordination with other processes during cell division… Expand
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Highly Cited
2007
Highly Cited
2007
Mcm4 (minichromosome maintenance–deficient 4 homolog) encodes a subunit of the MCM2-7 complex (also known as MCM2–MCM7), the… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective… Expand
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Highly Cited
2006
Highly Cited
2006
Cdc7 kinase, conserved from yeasts to human, plays important roles in DNA replication. However, the mechanisms by which it… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Antifungal agents exert their activity through a variety of mechanisms, some of which are poorly understood. We examined… Expand
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Highly Cited
1997
Highly Cited
1997
  • Y. Ishimi
  • The Journal of Biological Chemistry
  • 1997
  • Corpus ID: 20853775
All six minichromosome maintenance (MCM) proteins have DNA-dependent ATPase motifs in the central domain which is conserved from… Expand
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Highly Cited
1996
Highly Cited
1996
Members of the Mcm-protein family have recently been shown to be involved in restricting DNA replication to a single cycle in… Expand
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