MCI 186

Known as: MCI-186 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2016
051019882016

Papers overview

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2006
2006
The reactive oxygen species and Ca2+ overload play a critical role in ischemia/reperfusion (I/R) injury. MCI-186 has potent… (More)
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2004
2004
The present study was aimed to evaluate the effect of the free radical scavenger Edaravone on infarct volume due to permanent MCA… (More)
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2003
2003
Reperfusion after a period of ischemia is associated with the formation of reactive oxygen species (ROS) and Ca2+ overload… (More)
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2002
2002
We observed that 3-methyl-1-1phenyl-2-pyrazolin-5-one (MCI-186), a newly-developed free radical scavenger, attenuated necrosis in… (More)
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2000
2000
The bioactivity of 3-methyl-1-phenyl-pyrazolin-5-one (MCI-186) was examined based on histochemical changes in drastic global… (More)
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1998
1998
1. In this study, we investigated the effect of a radical scavenger, MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one), on cerebral… (More)
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1996
1996
MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one) is a newly developed antioxidant which has been shown to reduce brain edema in… (More)
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Highly Cited
1994
Highly Cited
1994
The anti-ischemic effects and a possible mechanism of a new antistroke agent, 3-methyl-1-phenyl-pyrazolin-5-one (MCI-186), were… (More)
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Highly Cited
1989
Highly Cited
1989
We induced brain edema in 72 rats by injecting 5 microliters of 3.0% wt:vol polyvinyl acetate into the left internal carotid… (More)
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1988
1988
Using cultured bovine aortic endothelial cells, the effects of MCI-186, a radical scavenger, were studied on arachidonic acid… (More)
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