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MCI 186

Known as: MCI-186 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Abstract Our objective was to confirm the efficacy and safety of edaravone in amyotrophic lateral sclerosis (ALS) patients. We… Expand
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Highly Cited
2004
Highly Cited
2004
The present study was aimed to evaluate the effect of the free radical scavenger Edaravone on infarct volume due to permanent MCA… Expand
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Highly Cited
2003
Highly Cited
2003
Edaravone, a novel free radical scavenger, demonstrates neuroprotective effects by inhibiting vascular endothelial cell injury… Expand
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2003
2003
Edaravone, a novel free radical scavenger, demonstrates neuroprotective effects by inhibiting vascular endothelial cell injury… Expand
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2002
2002
We observed that 3-methyl-1-1phenyl-2-pyrazolin-5-one (MCI-186), a newly-developed free radical scavenger, attenuated necrosis in… Expand
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Highly Cited
1997
Highly Cited
1997
We investigated the effects of a free radical scavenger, 3-methyl-1-phenyl-2-pyrazolin-5-one (MCl-186), on infarct areas… Expand
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Highly Cited
1994
Highly Cited
1994
The anti-ischemic effects and a possible mechanism of a new antistroke agent, 3-methyl-1-phenyl-pyrazolin-5-one (MCI-186), were… Expand
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Highly Cited
1989
Highly Cited
1989
We induced brain edema in 72 rats by injecting 5 microliters of 3.0% wt:vol polyvinyl acetate into the left internal carotid… Expand
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Highly Cited
1988
Highly Cited
1988
Using cultured bovine aortic endothelial cells, the effects of MCI-186, a radical scavenger, were studied on arachidonic acid… Expand
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Highly Cited
1988
Highly Cited
1988
Regional changes in the amount of free fatty acids, polyphosphoinositides, and water content in the cerebral cortex were examined… Expand
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