Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

MCI 186

Known as: MCI-186 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Edaravone is a low-molecular-weight antioxidant drug targeting peroxyl radicals among many types of reactive oxygen species… Expand
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Highly Cited
2014
Highly Cited
2014
Abstract Our objective was to confirm the efficacy and safety of edaravone in amyotrophic lateral sclerosis (ALS) patients. We… Expand
Highly Cited
2003
Highly Cited
2003
Edaravone, a novel free radical scavenger, demonstrates neuroprotective effects by inhibiting vascular endothelial cell injury… Expand
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Highly Cited
2003
Highly Cited
2003
  • E. Otomo
  • Cerebrovascular diseases
  • 2003
  • Corpus ID: 46753875
Edaravone, a novel free radical scavenger, demonstrates neuroprotective effects by inhibiting vascular endothelial cell injury… Expand
Highly Cited
2002
Highly Cited
2002
We observed that 3-methyl-1-1phenyl-2-pyrazolin-5-one (MCI-186), a newly-developed free radical scavenger, attenuated necrosis in… Expand
Highly Cited
1997
Highly Cited
1997
We investigated the effects of a free radical scavenger, 3-methyl-1-phenyl-2-pyrazolin-5-one (MCl-186), on infarct areas… Expand
Highly Cited
1994
Highly Cited
1994
The anti-ischemic effects and a possible mechanism of a new antistroke agent, 3-methyl-1-phenyl-pyrazolin-5-one (MCI-186), were… Expand
Highly Cited
1989
Highly Cited
1989
We induced brain edema in 72 rats by injecting 5 microliters of 3.0% wt:vol polyvinyl acetate into the left internal carotid… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
1988
Highly Cited
1988
Using cultured bovine aortic endothelial cells, the effects of MCI-186, a radical scavenger, were studied on arachidonic acid… Expand
Highly Cited
1988
Highly Cited
1988
Regional changes in the amount of free fatty acids, polyphosphoinositides, and water content in the cerebral cortex were examined… Expand
  • figure 1
  • table 1
  • figure 2
  • table 1
  • figure 3