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Development of hepatic sinusoidal structure with special reference to the Ito cells
- H. Enzan, H. Himeno, Mayumi Hiroi, H. Kiyoku, T. Saibara, S. Onishi
- Medicine, Biology
- Microscopy research and technique
- 15 November 1997
To elucidate sinusoidal cell structure and function under normal conditions and their behavior in diseased settings, an understanding of their developmental aspects is needed.
Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in non-alcoholic steatohepatitis.
- Chikako Namikawa, Zhang Shu-ping, +8 authors S. Onishi
- Biology, Medicine
- Journal of hepatology
- 1 May 2004
BACKGROUND/AIMS The pathogenesis of non-alcoholic steatohepatitis (NASH) is poorly understood. The aim of this study was to examine genetic influences on NASH pathogenesis. METHODS Blood samples… Expand
Predictive factors for esophageal stenosis after endoscopic submucosal dissection for superficial esophageal cancer.
- H. Mizuta, I. Nishimori, Y. Kuratani, Y. Higashidani, T. Kohsaki, S. Onishi
- Diseases of the esophagus : official journal of…
- 1 October 2009
Endoscopic submucosal dissection (ESD) has been utilized as an alternative treatment to endoscopic mucosal resection for superficial esophageal cancer. We aimed to evaluate the complications… Expand
Identification of carbonic anhydrase IV and VI mRNA expression in human pancreas and salivary glands.
Cytoplasmic carbonic anhydrase (CA) II is involved in acid-base balance in a wide variety of tissues. Extracellular CAs, membrane-bound CA IV and excretory CA VI, play a cooperative role with CA II… Expand
Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis
Nonalcoholic steatohepatitis (NASH) is now the most frequent cause of chronic liver impairment in developed countries and is a suggested causative factor in the development of cryptogenic cirrhosis… Expand
[Diagnosis of and therapy for nonalcoholic steatohepatitis].
Serum antibodies to carbonic anhydrase I and II in patients with idiopathic chronic pancreatitis and Sjögren's syndrome.
BACKGROUND & AIMS Patients with idiopathic chronic pancreatitis and Sjögren's syndrome show immune responses against a 60-kilodalton protein isolated from human pancreas extracts. Monoclonal antibody… Expand
Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.
- I. Nishimori, Tomoko Minakuchi, +5 authors C. Supuran
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 1 July 2007
DNA clones for the beta-class carbonic anhydrase (CA, EC 220.127.116.11) of Helicobactor pylori (hpbetaCA) were obtained. A recombinant hpbetaCA protein lacking the N-terminal 15-amino acid residues was… Expand
High levels of ezrin expressed by human pancreatic adenocarcinoma cell lines with high metastatic potential.
- N. Akisawa, I. Nishimori, T. Iwamura, S. Onishi, M. Hollingsworth
- Chemistry, Medicine
- Biochemical and biophysical research…
- 10 May 1999
Ezrin is a membrane cytoskeleton crosslinker protein that is a member of the ERM (ezrin/radixin/moesin) family. Ezrin binds adhesion molecules such as CD43, CD44, ICAM-1, and ICAM-2, which are… Expand
The efficacy of ursodeoxycholic acid and bezafibrate combination therapy for primary biliary cirrhosis: A prospective, multicenter study
- S. Iwasaki, H. Ohira, +9 authors G. Toda
- Hepatology research : the official journal of the…
- 1 June 2008
Aim: Treatment with ursodeoxycholic acid (UDCA) improves the survival of stage I and II primary biliary cirrhosis (PBC) patients. However, new therapeutic options are needed for patients who are… Expand