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MAX Interacting Protein 1

Known as: MAX Dimerization Protein 2, MXI1-0 protein, human, bHLHc11 
Max-interacting protein 1 (228 aa, ~26 kDa) is encoded by the human MXI1 gene. This protein plays a role in transcription factor binding and… 
National Institutes of Health

Related topics

Related topics

24 relations

Broader (2)

Basic Helix-Loop-Helix Transcription FactorsTumor Suppressor Proteins
BrainCell NucleusCell Proliferation Regulatory ProcessDNA-Binding Proteins

Papers overview

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2007
2007
Expression and mutation analysis of genes that encode the Myc antagonists Mad1, Mxi1 and Rox in acute leukaemia
The Myc antagonists Mad1, Mxi1 and Rox proteins share two highly conserved domains, Sin3-interacting domain (SID) and basic helix… 
2004
2004
Autoregulation of the N‐myc gene is operative in neuroblastoma and involves histone deacetylase 2
Autoregulation of the myc gene family is a negative feedback mechanism known to occur at high levels of Myc expression. Loss of… 
Review
1999
Review
1999
Two MAD tails: what the recent knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network.
1999
1999
Max interacting protein 1: loss of heterozygosity is frequent in desmoplastic melanoma.
Max interacting protein 1 (MXI1), a negative regulator of myc oncoprotein with tumor suppressor properties, has been mapped to… 
1997
1997
Expression and subcellular localization of the Myc superfamily proteins: c-Myc, Max, Mad1 and Mxi1 in the epiphyseal plate cartilage chondrocytes of growing rats.
The changes in the expressions of the protooncogene protein c-Myc, its dimerization partner Max and the competitive inhibitors… 
Review
1997
Review
1997
Regulated expression and function of the c-Myc antagonist, Mad1, during a molecular switch from proliferation to differentiation.
Myc, Max, Mad, Mxi1 and mSin3 comprise a transcription factor superfamily in which the central protein is Max. All family members… 
1996
1996
Overexpression of Mxi1 inhibits the induction of the human ornithine decarboxylase gene by the Myc/Max protein complex.
We have previously shown that the Myc/Max protein complex plays a role in the growth-associated expression of the human ornithine… 
1996
1996
Mxi1 tumor suppressor gene is not mutated in primary pancreatic adenocarcinoma.
1995
1995
Differential expression of c-myc, max and mxi1 in human myeloid leukemia cells during retrodifferentiation and cell death.
1994
1994
Evolutionary relationships and functional conservation among vertebrate Max-associated proteins: the zebra fish homolog of Mxi1.
In mammals, current evidence supports the view that Myc-responsive activities are regulated in part through an intracellular… 
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