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Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study
Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format forExpand
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Pancreatic cyst fluid DNA analysis in evaluating pancreatic cysts: a report of the PANDA study.
BACKGROUND The role of pancreatic cyst fluid DNA analysis in evaluating pancreatic cysts remains unclear. OBJECTIVE Our purpose was to evaluate the utility of a detailed DNA analysis of pancreaticExpand
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The relationship between TP53 mutations and overexpression of p53 and prognosis in malignant gliomas of childhood.
The prognosis for children with high-grade gliomas remains somewhat unpredictable. Although prolonged disease control is sometimes achieved after surgery, radiotherapy, and chemotherapy, mostExpand
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Molecular genotyping of BK and JC viruses in human polyomavirus-associated interstitial nephritis after renal transplantation.
The human polyomaviruses BK virus (BKV) and JC virus (JCV) have been linked to ureteric stenosis and allograft interstitial nephritis, but molecular characterization of the species involved has notExpand
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Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K‐ras‐2 mutation type
Background. New measures enabling better prediction of biologic behavior of large bowel cancer are highly desirable. One hundred ninety‐four consecutive primary, recurrent, and metastatic colorectalExpand
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Increased expression of keratinocyte growth factor messenger RNA associated with inflammatory bowel disease.
BACKGROUND & AIMS Alterations in intestinal epithelial cell function are common in inflammatory bowel disease (IBD). Keratinocyte growth factor (KGF) is an epithelial cell-specific mitogen. The aimExpand
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Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood: results from the Children's Cancer Group 945 cohort.
OBJECT In reporting on molecular studies involving malignant gliomas in adults, authors have noted that deletions of PTEN and amplification of EGFR are common and may contribute to tumor development,Expand
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Expression of p53 and prognosis in children with malignant gliomas.
BACKGROUND The prognosis of children with high-grade gliomas is uncertain, even when clinical and histologic findings are considered. We investigated whether mutations in the TP53 gene or the degreeExpand
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Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival.
The goal of this study was to determine whether a panel of tumor suppressor gene markers of allelic loss could serve as a representative indicator of gene damage and thereby provide furtherExpand
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Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors. Correlation with histological subtype and clinical outcome.
Neuroendocrine tumors of lung, including typical carcinoid (TC), atypical carcinoid (AC), large cell neuroendocrine carcinoma (LCNEC), and small cell lung carcinoma (SCLC) constitute a spectrum ofExpand
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