MAPT gene

Known as: microtubule associated protein tau, PPP1R103, protein phosphatase 1, regulatory subunit 103 
This gene may be involved in the mediation of neuronal polarity.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Parkinson disease (PD) is a chronic neurodegenerative disorder with a cumulative prevalence of greater than one per thousand. To… (More)
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Highly Cited
2008
Highly Cited
2008
Using comparative sequencing approaches, we investigated the evolutionary history of the European-enriched 17q21.31 MAPT… (More)
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Highly Cited
2007
Highly Cited
2007
Previously we have shown that the H1c haplotype on the background of the H1 clade of haplotypes at the MAPT locus is associated… (More)
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Highly Cited
2006
Highly Cited
2006
Frontotemporal dementia (FTD) is the second most common cause of dementia in people under the age of 65 years. A large proportion… (More)
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Highly Cited
2006
Highly Cited
2006
Recently, the application of array-based comparative genomic hybridization (array CGH) has improved rates of detection of… (More)
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Highly Cited
2006
Highly Cited
2006
Frontotemporal dementia (FTD) with ubiquitin-immunoreactive neuronal inclusions (both cytoplasmic and nuclear) of unknown nature… (More)
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Highly Cited
1998
Highly Cited
1998
Frontotemporal dementia with parkinsonism, chromosome 17 type (FTDP-17), a recently defined disease entity, is clinically… (More)
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Highly Cited
1998
Highly Cited
1998
Familial multiple system tauopathy with presenile dementia (MSTD) is a neurodegenerative disease with an abundant filamentous tau… (More)
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Highly Cited
1996
Highly Cited
1996
Although cyclin-dependent kinase 5 (Cdk5) is closely related to other cyclin-dependent kinases, its kinase activity is detected… (More)
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Highly Cited
1986
Highly Cited
1986
A monoclonal antibody to the microtubule-associated protein tau (tau) labeled some neurofibrillary tangles and plaque neurites… (More)
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