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Microtubule-Associated Protein Tau

Known as: PHF-Tau, Microtubule Associated Protein Tau, Tau Protein 
Microtubule-associated protein tau (758 aa, ~79 kDa) is encoded by the human MAPT gene. This protein may be involved in axon stability.
National Institutes of Health

Related topics

Related topics

15 relations
Alzheimer's DiseaseCell MovementCytokinesisCytoskeletal Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Intramolecular pnicogen interactions in PHF-(CH2)(n)-PHF (n=2-6) systems.
A computational study of the intramolecular pnicogen bond in PHF-(CH2)n-PHF (n=2-6) systems was carried out. For each compound… 
2009
2009
Oxidized and phosphorylated synthetic peptides corresponding to the second and third tubulin-binding repeats of the tau protein reveal structural features of paired helical filament assembly.
The microtubule-associated protein tau of normal brains is attached to tubulin through its 18-amino-acid repeat units. In the… 
2005
2005
Modelling of amyloid β-peptide induced lesions using roller-drum incubation of hippocampal slice cultures from neonatal rats
Pronounced neurodegeneration of hippocampal pyramidal neurons has been shown in Alzheimer’s disease. The aim of this study was to… 
1997
1997
The neurofilament antibody RT97 recognises a developmentally regulated phosphorylation epitope on microtubule‐associated protein 1B
Microtubules are important for the growth and maintenance of stable neuronal processes and their organisation is controlled… 
1996
1996
Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer’s disease brains: double-labeling immunohistochemical study
Abstract The immunolocalization of presenilin in human brain was studied using two antibodies raised against different portions… 
1996
1996
Dephosphorylation studies of SKNSH-SY 5Y cell Tau proteins by endogenous phosphatase activity
1995
1995
Differential expression of exons 10 and 11 in normal tau and tau associated with paired helical filaments
Antibodies were raised to two synthetic peptides with amino acid sequences encoded by a variable region of exons 10 and 11 of the… 
1993
1993
Locations and immunoreactivities of phosphorylation sites on bovine and porcine tau proteins and a PHF-tau fragment.
1992
1992
The pathology of the neuronal cytoskeleton in Alzheimer's disease.
Highly Cited
1988
Highly Cited
1988
Phylogenetic conservation of brain microtubule-associated proteins MAP2 and TAU
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