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MAPK9 gene

Known as: Jun kinase, SAPK, MAPK9 
This gene plays a role in apoptosis, cell differentiation and regulation of transcription during the cellular response to stress.
National Institutes of Health

Related topics

Related topics

12 relations
ApoptosisCell Cycle ControlCell Differentiation processJUN kinase

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MAPK9 wt Allele

Papers overview

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2009
2009
Basal Cancer Cell Survival Involves JNK2 Suppression of a Novel JNK1/c-Jun/Bcl-3 Apoptotic Network
Background The regulation of apoptosis under basal (non-stress) conditions is crucial for normal mammalian development and also… 
2005
2005
Cross-talk between JIP3 and JIP1 during Glucose Deprivation
We have previously observed that glucose deprivation activates the ASK1-MEK-MAPK signal transduction pathway. In the present… 
Highly Cited
2005
Highly Cited
2005
Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway.
IFN-gamma and TNF-alpha are major proinflammatory cytokines implicated in islet beta-cell destruction, which results in type-1… 
2004
2004
Stress Induces Mitochondria-mediated Apoptosis Independent of SAPK/JNK Activation in Embryonic Stem Cells*
SAPK/JNK, which belongs to the family of mitogen-activated protein kinase (MAPK), is activated by many types of cellular stresses… 
Highly Cited
2003
Highly Cited
2003
Aluminum-induced apoptosis in cultured cortical neurons and its effect on SAPK/JNK signal transduction pathway
Highly Cited
2001
Highly Cited
2001
Transient Activation of Jun N-terminal Kinases and Protection from Apoptosis by the Insulin-like Growth Factor I Receptor Can Be Suppressed by Dicumarol*
The insulin-like growth factor I receptor (IGF-IR) activated by its ligands insulin-like growth factor (IGF)-I or IGF-II mediates… 
Highly Cited
1999
Highly Cited
1999
Delayed neuronal cell death in the rat hippocampus is mediated by the mitogen-activated protein kinase signal transduction pathway
Highly Cited
1998
Highly Cited
1998
Differential expression of SAPK isoforms in the rat brain. An in situ hybridisation study in the adult rat brain and during post-natal development.
Highly Cited
1997
Highly Cited
1997
Impaired CD28-mediated Interleukin 2 Production and Proliferation in Stress Kinase SAPK/ERK1 Kinase (SEK1)/Mitogen-activated Protein Kinase Kinase 4 (MKK4)-deficient T Lymphocytes
The dual specific kinase SAPK/ERK1 kinase (SEK1; mitogen-activated protein kinase kinase 4/Jun NH2 terminal kinase [ JNK] kinase… 
Highly Cited
1996
Highly Cited
1996
Selective response of ternary complex factor Sap1a to different mitogen-activated protein kinase subgroups.
Mitogenic and stres signals results in the activation of extracellular signal-regulated kinases (ERKs) and stress-activated… 
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