MAPK9 gene

Known as: Jun kinase, SAPK, MAPK9 
This gene plays a role in apoptosis, cell differentiation and regulation of transcription during the cellular response to stress.
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
FDH (10-formyltetrahydrofolate dehydrogenase) is strongly downregulated in tumors while its elevation suppresses proliferation of… (More)
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2002
2002
The c-Jun N-terminal kinases (JNKs) are activated by a variety of stress inducing agents and are thought to regulate apoptosis in… (More)
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Highly Cited
2000
Highly Cited
2000
Activation of the stress-activated protein kinase (SAPK/JNK) by genotoxic agents is necessary for induction of apoptosis. We… (More)
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2000
2000
Heme oxygenase-1 (HO), the heat shock/stress cognate of the heat shock protein 32 (HSP32) family of proteins, is postulated to be… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The Jun N-terminal kinase (JNK) signaling pathway has been implicated in cell proliferation and apoptosis, but its… (More)
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Highly Cited
1999
Highly Cited
1999
The breast cancer susceptibility gene BRCA1 encodes a protein implicated in the cellular response to DNA damage, with postulated… (More)
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Highly Cited
1998
Highly Cited
1998
The resistance to stress-induced apoptosis conferred by the thermotolerant state or by exogenous expression of HSP72 was measured… (More)
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Highly Cited
1997
Highly Cited
1997
The stress-activated protein kinases (SAPKs), also known as c-Jun amino-terminal kinases (JNKs), are activated in response to… (More)
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Highly Cited
1997
Highly Cited
1997
The dual specific kinase SAPK/ERK1 kinase (SEK1; mitogen-activated protein kinase kinase 4/Jun NH2 terminal kinase [ JNK] kinase… (More)
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1996
1996
Because the catalytic domain of dual leucine zipper-bearing kinase (DLK) bears sequence similarity to members of the mitogen… (More)
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