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MAPK9 wt Allele

Known as: JNK-55, JNK2, JNK2Alpha 
Human MAPK9 wild-type allele is located within 5q35 and is approximately 45 kb in length. This allele, which encodes mitogen-activated protein kinase… 
National Institutes of Health

Related topics

Related topics

22 relations
5q35Adipocytokine Signaling PathwayApoptosisCell Cycle Control

Broader (1)

MAPK9 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Knockout of c-Jun N-terminal kinases 1, 2 or 3 isoforms induces behavioural changes
Highly Cited
2012
Highly Cited
2012
Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation
Ras is one of the most frequently activated oncogenes in cancer. Two mitogen-activated protein kinases (MAPKs) are important for… 
2012
2012
JNK3 Maintains Expression of the Insulin Receptor Substrate 2 (IRS2) in Insulin-Secreting Cells: Functional Consequences for Insulin Signaling
We have recently shown that silencing of the brain/islet specific c-Jun N-terminal Kinase3 (JNK3) isoform enhances both basal and… 
2010
2010
JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells.
BACKGROUND Multidrug resistance (MDR) is extremely common in hepatocellular carcinoma (HCC) and is a major problem in cancer… 
2009
2009
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits
RNA polymerase (pol) III-dependent transcription is subject to stringent regulation by tumor suppressors and oncogenic proteins… 
2008
2008
The crystal structure of JNK2 reveals conformational flexibility in the MAP kinase insert and indicates its involvement in the regulation of catalytic activity.
2007
2007
Mouse Neutrophils Require JNK2 MAPK for Toxoplasma gondii-Induced IL-12p40 and CCL2/MCP-1 Release1
The MAPK family member JNK/stress-activated MAPK (SAPK) is involved in extracellular stress and proinflammatory cytokine… 
2007
2007
JNK2 negatively regulates CD8+ T cell effector function and anti‐tumor immune response
JNK1 and JNK2 have distinct effects on activation, differentiation and function of CD8+ T cells. Our early studies demonstrated… 
2006
2006
Coordination of JNK1 and JNK2 Is Critical for GADD45α Induction and Its Mediated Cell Apoptosis in Arsenite Responses*
Arsenite is a well documented environmental pathogen, whereas it has also been applied as medication to treat various neoplasmas… 
2001
2001
NGF stimulation increases JNK2 phosphorylation and reduces caspase-3 activity in the olfactory bulb of estrogen-replaced animals.
Estrogen receptors are extensively colocalized with neurotrophins and their receptors in the rodent forebrain. We have shown… 
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