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MAP3K10 gene

Known as: MLK2, SERINE/THREONINE KINASE, MKN28-DERIVED, NONRECEPTOR-TYPE, MKN28 KINASE 
National Institutes of Health

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MAP3K10 protein, human

Papers overview

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2013
2013
MAP3K10 promotes the proliferation and decreases the sensitivity of pancreatic cancer cells to gemcitabine by upregulating Gli-1 and Gli-2.
2011
2011
Cloning and Initial Functional Characterization of Mlk4α and Mlk4β
We have cloned a novel human mixed-lineage kinase gene, MLK4. Two alternatively spliced forms, MLK4α (580 aa) and MLK4β (1036 aa… 
2009
2009
Mixed lineage kinase 2 and hippocalcin are localized in Lewy bodies of Parkinson's disease
Highly Cited
2007
Highly Cited
2007
Dissection of a Signaling Pathway by Which Pathogen-associated Molecular Patterns Recruit the JNK and p38 MAPKs and Trigger Cytokine Release*
Pathogen-associated molecular patterns (PAMPs), molecular moieties produced by invading microbial pathogens, initiate innate… 
2003
2003
PAK interacts with NCK and MLK2 to regulate the activation of jun N‐terminal kinase
2003
2003
A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation.
2003
2003
Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors
1999
1999
Expression of mixed lineage kinase 2 in germ cells of the testis
Mixed Lineage Kinase 2 is a mammalian protein kinase that activates stress‐activated protein kinases/c‐jun N‐terminal kinases… 
1998
1998
Two‐dimensional electrophoretic analysis of mixed lineage kinase 2 N‐terminal domain binding proteins
The mixed lineage kinase 2 (MLK2) protein contains several structurally distinct domains including an src homology (SH) 3 domain… 
1997
1997
Two‐dimensional electrophoretic analysis of human breast carcinoma proteins: Mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2
MLK2, a member of the mixed lineage kinase (MLK) family of protein kinases, first reported by Dorow et al. (Eur. J. Biochem. 1993… 
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