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MAP3K10 gene

Known as: MLK2, SERINE/THREONINE KINASE, MKN28-DERIVED, NONRECEPTOR-TYPE, MKN28 KINASE 
National Institutes of Health

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MAP3K10 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells
HIV-1 insertions targeting BACH2 or MLK2 are enriched and persist for decades in hematopoietic cells from patients under… Expand
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2013
2013
Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity.
Saturated free fatty acid (FFA) is implicated in the metabolic response to obesity. In vitro studies indicate that FFA signaling… Expand
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Highly Cited
2008
Highly Cited
2008
Application of Active and Kinase-Deficient Kinome Collection for Identification of Kinases Regulating Hedgehog Signaling
To allow genome-scale identification of genes that regulate cellular signaling, we cloned >90% of all human full-length protein… Expand
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Highly Cited
2007
Highly Cited
2007
Dissection of a Signaling Pathway by Which Pathogen-associated Molecular Patterns Recruit the JNK and p38 MAPKs and Trigger Cytokine Release*
Pathogen-associated molecular patterns (PAMPs), molecular moieties produced by invading microbial pathogens, initiate innate… Expand
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2003
2003
PAK interacts with NCK and MLK2 to regulate the activation of jun N‐terminal kinase
The p21‐GTPase activated kinase, PAK1, and the mixed lineage kinase, MLK2, have been implicated in the activation of jun N… Expand
Highly Cited
2001
Highly Cited
2001
Kainate Receptor Activation Induces Mixed Lineage Kinase-mediated Cellular Signaling Cascades via Post-synaptic Density Protein 95*
Kainate receptor glutamate receptor 6 (GluR6) subunit-deficient and c-Jun N-terminal kinase 3 (JNK3)-null mice share similar… Expand
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Highly Cited
2001
Highly Cited
2001
Autoinhibition of Mixed Lineage Kinase 3 through Its Src Homology 3 Domain*
Mixed lineage kinase 3 (MLK3) is a serine/threonine protein kinase that functions as a mitogen-activated protein kinase kinase… Expand
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Highly Cited
1998
Highly Cited
1998
The MAP kinase kinase kinase MLK2 co‐localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3
The MLK (mixed lineage) ser/thr kinases are most closely related to the MAP kinase kinase kinase family. In addition to a kinase… Expand
1997
1997
Two‐dimensional electrophoretic analysis of human breast carcinoma proteins: Mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2
MLK2, a member of the mixed lineage kinase (MLK) family of protein kinases, first reported by Dorow et al. (Eur. J. Biochem. 1993… Expand
1995
1995
Cloning and characterization of MST, a novel (putative) serine/threonine kinase with SH3 domain.
Protein kinases play a key role in cell growth regulation. We have isolated a cDNA fragment of the MST gene from the MKN28… Expand
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