Lymphocyte Activation

Known as: Transformation, Lymphoblast, Lymphocyte Activation Process, activation lymphocyte 
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide… (More)

Topic mentions per year

Topic mentions per year

1954-2017
010020030019542016

Papers overview

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Highly Cited
2012
Highly Cited
2012
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism, and… (More)
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Highly Cited
2011
Highly Cited
2011
To fulfill the bioenergetic and biosynthetic demand of proliferation, T cells reprogram their metabolic pathways from fatty acid… (More)
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Highly Cited
2002
Highly Cited
2002
Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine proteases called caspases. In the… (More)
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Highly Cited
2000
Highly Cited
2000
PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Mice deficient in PD-1 exhibit a… (More)
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Highly Cited
2000
Highly Cited
2000
BCL-6, a transcriptional repressor frequently translocated in lymphomas, regulates germinal center B cell differentiation and… (More)
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Highly Cited
2000
Highly Cited
2000
The signalling thresholds of antigen receptors and co-stimulatory receptors determine immunity or tolerance to self molecules… (More)
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Highly Cited
1999
Highly Cited
1999
To define predictors of survival time in late human immunodeficiency virus type 1 (HIV-1) disease, long- and short-duration… (More)
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Highly Cited
1996
Highly Cited
1996
While chemokines primarily promote chemotaxis, it is apparent that these cytokines also modulate a number of other biologic… (More)
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Highly Cited
1995
Highly Cited
1995
Biochemical studies of signaling mediated by many cytokine and growth factor receptors have implicated members of the Jak family… (More)
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Highly Cited
1989
Highly Cited
1989
Interaction of antigen in the proper histocompatibility context with the T lymphocyte antigen receptor leads to an orderly series… (More)
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