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Lymphocyte Activation

Known as: Transformation, Lymphoblast, Lymphocyte Activation Process, activation lymphocyte 
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide… 
National Institutes of Health

Related topics

Related topics

29 relations
Aerosolized AldesleukinAldesleukinAntigen-Presenting CellsAntigens

Narrower (3)

Lymphocyte transformation, mitogen (phytomitogen) or antigen induced blastogenesis (procedure)establishment of lymphocyte polarityimmunological synapse formation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
cFLIP regulation of lymphocyte activation and development
Cellular caspase-8 (FLICE)-like inhibitory protein (cFLIP) was originally identified as an inhibitor of death-receptor signalling… 
Highly Cited
2006
Highly Cited
2006
Leptin Receptor Expression and Signaling in Lymphocytes: Kinetics During Lymphocyte Activation, Role in Lymphocyte Survival, and Response to High Fat Diet in Mice1
Leptin has direct effects not only on neuroendocrine function and metabolism, but also on T cell-mediated immunity. We report in… 
Highly Cited
2003
Highly Cited
2003
Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase
Paracaspase (MALT1), a member of an evolutionarily conserved superfamily of caspase-like proteins, has been shown to bind and… 
Highly Cited
2002
Highly Cited
2002
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation
T lymphocytes are defective in cystine uptake and thus require exogenous thiols for activation and function. Here we show that… 
Highly Cited
2002
Highly Cited
2002
Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-31
Lymphocyte activation gene (LAG)-3 (CD223) is a CD4-related activation-induced cell surface molecule that binds to MHC class II… 
Highly Cited
2000
Highly Cited
2000
Germline transformation of the silkworm Bombyx mori L. using a piggyBac transposon-derived vector
We have developed a system for stable germline transformation in the silkworm Bombyx mori L. using piggyBac, a transposon… 
Highly Cited
1999
Highly Cited
1999
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.
To define predictors of survival time in late human immunodeficiency virus type 1 (HIV-1) disease, long- and short-duration… 
Highly Cited
1995
Highly Cited
1995
Defects in B Lymphocyte Maturation and T Lymphocyte Activation in Mice Lacking Jak3
Biochemical studies of signaling mediated by many cytokine and growth factor receptors have implicated members of the Jak family… 
Review
1985
Review
1985
Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester
Although it has been proposed that the activation of T lymphocytes is mediated by an early rise in cytosolic calcium… 
Highly Cited
1985
Highly Cited
1985
Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition.
We studied purified subpopulations of lymphocytes from patients with the acquired immunodeficiency syndrome (AIDS) in order to… 
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