FAQ

immunological synapse formation

Known as: formation of immunological synapse 
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of… (More)

Topic mentions per year

Topic mentions per year

2000-2016
051020002016

Related topics

Related topics

1 relation

Broader (1)

Lymphocyte Activation

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
immunological synapse formation
Lymphocyte Activation

Papers overview

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Highly Cited
2008
Highly Cited
2008
Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug.
Cancer is associated with immune deficiency, but the biologic basis of this is poorly defined. Here we demonstrate that impaired… (More)
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2008
2008
Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation.
Upon antigen recognition, T-cell receptor (TCR/CD3) and other signaling molecules become enriched in a specialized contact site… (More)
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Highly Cited
2007
Highly Cited
2007
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.
T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a… (More)
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Highly Cited
2005
Highly Cited
2005
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation.
T cell shape is dictated by the selective recruitment of molecules to different regions of the cell (polarity) and is integral to… (More)
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2004
2004
Cofilin peptide homologs interfere with immunological synapse formation and T cell activation.
The formation of supramolecular activation clusters within the immunological synapse, crucial for sustained signaling and T… (More)
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2003
2003
Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling.
The activation of biological T cell responses requires prolonged contact with APCs and sustained signaling. We investigated… (More)
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Highly Cited
2003
Highly Cited
2003
Cutting edge: dendritic cell actin cytoskeletal polarization during immunological synapse formation is highly antigen-dependent.
Dendritic cells (DC) actively rearrange their actin cytoskeleton to participate in formation of the immunological synapse (IS… (More)
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Highly Cited
2002
Highly Cited
2002
T cell receptor signaling precedes immunological synapse formation.
The area of contact between a T cell and an antigen-presenting cell (APC) is known as the immunological synapse. Although its… (More)
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2002
2002
Live-cell dynamics and the role of costimulation in immunological synapse formation.
Using transfected fibroblasts expressing both wild-type I-E(k) and green fluorescent protein-tagged I-E(k) with covalently… (More)
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Highly Cited
2001
Highly Cited
2001
Synaptic pattern formation during cellular recognition.
Cell-cell recognition often requires the formation of a highly organized pattern of receptor proteins (a synapse) in the… (More)
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