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immunological synapse formation

Known as: formation of immunological synapse 
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of… Expand
National Institutes of Health

Papers overview

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2014
2014
Human respiratory syncytial virus (hRSV) is the leading cause of bronchiolitis and pneumonia in young children worldwide. The… Expand
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Highly Cited
2012
Highly Cited
2012
Actin retrograde flow and actomyosin II contraction have both been implicated in the inward movement of T cell receptor (TCR… Expand
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Highly Cited
2008
Highly Cited
2008
Upon antigen recognition, T-cell receptor (TCR/CD3) and other signaling molecules become enriched in a specialized contact site… Expand
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Highly Cited
2007
Highly Cited
2007
T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a… Expand
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Highly Cited
2007
Highly Cited
2007
HIV efficiently spreads in lymphocytes, likely through virological synapses (VSs). These cell-cell junctions share some… Expand
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Highly Cited
2006
Highly Cited
2006
T cell activation in vivo occurs in a lymphoid milieu that presents chemotactic and T cell receptor signals concurrently. Here we… Expand
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Highly Cited
2005
Highly Cited
2005
T cell shape is dictated by the selective recruitment of molecules to different regions of the cell (polarity) and is integral to… Expand
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Highly Cited
2003
Highly Cited
2003
The activation of biological T cell responses requires prolonged contact with APCs and sustained signaling. We investigated… Expand
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Highly Cited
2002
Highly Cited
2002
The area of contact between a T cell and an antigen-presenting cell (APC) is known as the immunological synapse. Although its… Expand
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Highly Cited
1999
Highly Cited
1999
The specialized junction between a T lymphocyte and an antigen-presenting cell, the immunological synapse, consists of a central… Expand
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