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immunological synapse formation
Known as:
formation of immunological synapse
Â
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of…Â
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Topic mentions per year
Topic mentions per year
2000-2016
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2000
2016
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Broader (1)
Lymphocyte Activation
Related mentions per year
Related mentions per year
1954-2018
1960
1980
2000
2020
immunological synapse formation
Lymphocyte Activation
Papers overview
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Highly Cited
2008
Highly Cited
2008
Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug.
Alan G Ramsay
,
Amy J. Johnson
,
+5 authors
John G Gribben
The Journal of clinical investigation
2008
Cancer is associated with immune deficiency, but the biologic basis of this is poorly defined. Here we demonstrate that impaired…Â
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2008
2008
Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation.
Genaro Patiño-López
,
Xiaoyun Dong
,
+6 authors
Stephen Shaw
The Journal of biological chemistry
2008
Upon antigen recognition, T-cell receptor (TCR/CD3) and other signaling molecules become enriched in a specialized contact site…Â
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Highly Cited
2007
Highly Cited
2007
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.
Yoshihisa Kaizuka
,
Adam Douglass
,
Rajat Varma
,
Michael L. Dustin
,
Ronald D Vale
Proceedings of the National Academy of Sciences…
2007
T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a…Â
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Highly Cited
2005
Highly Cited
2005
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation.
Mandy J. Ludford-Menting
,
Jane Oliaro
,
+14 authors
Sarah M. Russell
Immunity
2005
T cell shape is dictated by the selective recruitment of molecules to different regions of the cell (polarity) and is integral to…Â
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2004
2004
Cofilin peptide homologs interfere with immunological synapse formation and T cell activation.
Sybille M Eibert
,
Kyeong-Hee Lee
,
+5 authors
Yvonne Samstag
Proceedings of the National Academy of Sciences…
2004
The formation of supramolecular activation clusters within the immunological synapse, crucial for sustained signaling and T…Â
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2003
2003
Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling.
Mustapha Faroudi
,
Rossana Zaru
,
Pierre Paulet
,
Sabina Mueller
,
S. Valitutti
Journal of immunology
2003
The activation of biological T cell responses requires prolonged contact with APCs and sustained signaling. We investigated…Â
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Highly Cited
2003
Highly Cited
2003
Cutting edge: dendritic cell actin cytoskeletal polarization during immunological synapse formation is highly antigen-dependent.
Monther M. Al-alwan
,
Robert Stefan Liwski
,
+4 authors
Kenneth West
Journal of immunology
2003
Dendritic cells (DC) actively rearrange their actin cytoskeleton to participate in formation of the immunological synapse (IS…Â
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Highly Cited
2002
Highly Cited
2002
T cell receptor signaling precedes immunological synapse formation.
Kyeong-Hee Lee
,
Amy D Holdorf
,
Michael L. Dustin
,
Andrew H. C. Chan
,
Paul. M. Allen
,
Andrey S.-Y. Shaw
Science
2002
The area of contact between a T cell and an antigen-presenting cell (APC) is known as the immunological synapse. Although its…Â
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2002
2002
Live-cell dynamics and the role of costimulation in immunological synapse formation.
Scott A. Wetzel
,
Timothy W. McKeithan
,
David C Parker
Journal of immunology
2002
Using transfected fibroblasts expressing both wild-type I-E(k) and green fluorescent protein-tagged I-E(k) with covalently…Â
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Highly Cited
2001
Highly Cited
2001
Synaptic pattern formation during cellular recognition.
Shu-yuan Qi
,
Jay T. Groves
,
A. K. Chakraborty
Proceedings of the National Academy of Sciences…
2001
Cell-cell recognition often requires the formation of a highly organized pattern of receptor proteins (a synapse) in the…Â
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