Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

immunological synapse formation

Known as: formation of immunological synapse 
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Lymphocyte Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells.
Human respiratory syncytial virus (hRSV) is the leading cause of bronchiolitis and pneumonia in young children worldwide. The… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells
Actin retrograde flow and actomyosin II contraction have both been implicated in the inward movement of T cell receptor (TCR… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation.
Upon antigen recognition, T-cell receptor (TCR/CD3) and other signaling molecules become enriched in a specialized contact site… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.
T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.
HIV efficiently spreads in lymphocytes, likely through virological synapses (VSs). These cell-cell junctions share some… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Surface-bound chemokines capture and prime T cells for synapse formation
T cell activation in vivo occurs in a lymphoid milieu that presents chemotactic and T cell receptor signals concurrently. Here we… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation.
T cell shape is dictated by the selective recruitment of molecules to different regions of the cell (polarity) and is integral to… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling.
The activation of biological T cell responses requires prolonged contact with APCs and sustained signaling. We investigated… Expand
  • figure 1
  • table I
  • figure 2
  • table II
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
T cell receptor signaling precedes immunological synapse formation.
The area of contact between a T cell and an antigen-presenting cell (APC) is known as the immunological synapse. Although its… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The immunological synapse: a molecular machine controlling T cell activation.
The specialized junction between a T lymphocyte and an antigen-presenting cell, the immunological synapse, consists of a central… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE