immunological synapse formation

Known as: formation of immunological synapse 
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of… (More)

Topic mentions per year

Topic mentions per year

2000-2016
051020002016

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cancer is associated with immune deficiency, but the biologic basis of this is poorly defined. Here we demonstrate that impaired… (More)
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2008
2008
Upon antigen recognition, T-cell receptor (TCR/CD3) and other signaling molecules become enriched in a specialized contact site… (More)
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Highly Cited
2007
Highly Cited
2007
T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a… (More)
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Highly Cited
2005
Highly Cited
2005
T cell shape is dictated by the selective recruitment of molecules to different regions of the cell (polarity) and is integral to… (More)
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2004
2004
The formation of supramolecular activation clusters within the immunological synapse, crucial for sustained signaling and T… (More)
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2003
2003
The activation of biological T cell responses requires prolonged contact with APCs and sustained signaling. We investigated… (More)
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Highly Cited
2003
Highly Cited
2003
Dendritic cells (DC) actively rearrange their actin cytoskeleton to participate in formation of the immunological synapse (IS… (More)
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Highly Cited
2002
Highly Cited
2002
The area of contact between a T cell and an antigen-presenting cell (APC) is known as the immunological synapse. Although its… (More)
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2002
2002
Using transfected fibroblasts expressing both wild-type I-E(k) and green fluorescent protein-tagged I-E(k) with covalently… (More)
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Highly Cited
2001
Highly Cited
2001
Cell-cell recognition often requires the formation of a highly organized pattern of receptor proteins (a synapse) in the… (More)
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