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Lupus Erythematosus, Systemic

Known as: SYNDROME DISSEMINATED LUPUS ERYTHEMATOSIS, LUPUS, ERYTHEMATOSUS, SYSTEMIC, Lupus Erythematosus Disseminatus 
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the… 
National Institutes of Health

Related topics

Related topics

50 relations
Antiphospholipid AntibodiesAntiphospholipid SyndromeArthritisAuranofin

Narrower (2)

Lupus NephritisLupus Vasculitis, Central Nervous System

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Mortality in systemic lupus erythematosus.
Many factors influence survival in systemic lupus erythematosus (SLE). Earlier diagnosis and advances in treatment have led to… 
Highly Cited
2005
Highly Cited
2005
Defective B cell tolerance checkpoints in systemic lupus erythematosus
A cardinal feature of systemic lupus erythematosus (SLE) is the development of autoantibodies. The first autoantibodies described… 
Highly Cited
2002
Highly Cited
2002
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population… 
Highly Cited
2001
Highly Cited
2001
Cutting Edge: A Role for B Lymphocyte Stimulator in Systemic Lupus Erythematosus1
Increased levels of B lymphocyte stimulator (BLyS) are associated with systemic autoimmunity in animal models of spontaneous… 
Highly Cited
1998
Highly Cited
1998
Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus.
OBJECTIVE To investigate whether the established impaired phagocyte function in systemic lupus erythematosus (SLE) patients also… 
Highly Cited
1991
Highly Cited
1991
Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis.
Elevated spontaneous IgG production is characteristic of SLE. To identify the factors that support it, IL-6, a cytokine with an… 
Highly Cited
1990
Highly Cited
1990
Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis.
Procainamide and hydralazine inhibit T cell DNA methylation and induce autoreactivity in cloned CD4+ T cells. These drugs also… 
Highly Cited
1987
Highly Cited
1987
Mortality in systemic lupus erythematosus.
OBJECTIVE To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort ever assembled. METHODS Our… 
Highly Cited
1979
Highly Cited
1979
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus.
Patients with systemic lupus erythematosus often possess antibodies against two nuclear antigens called Sm and RNP… 
Highly Cited
1967
Highly Cited
1967
IMMUNOLOGICAL STUDIES CONCERNING THE NEPHRITIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
Antibodies were eluted from the isolated glomeruli prepared from the kidneys of 10 patients with the nephritis of systemic lupus… 
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