Auranofin

Known as: (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate, 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold, Auranofin [Chemical/Ingredient] 
An orally available, lipophilic, organogold compound, used to treat rheumatoid arthritis, with anti-inflammatory and potential antineoplastic… (More)

Topic mentions per year

Topic mentions per year

1976-2018
020406019762018

Papers overview

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2015
2015
BACKGROUND/AIMS The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis… (More)
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2015
2015
Drug discovery, development and registration is an expensive and time-consuming process associated with a high failure rate… (More)
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2009
2009
Schistosomiasis is a parasitic disease affecting over 200 million people currently treated with one drug, praziquantel. A… (More)
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Highly Cited
2007
Highly Cited
2007
Cisplatin is an effective antitumor agent for the treatment of several carcinomas. However, the development of resistance to… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Schistosomiasis--infection with helminth parasites in the genus Schistosoma, including S. mansoni--is a widespread… (More)
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2007
2007
Auranofin (AF) is a sulphur-containing gold compound. Because of its anti-inflammatory and immunosuppressive activities, AF has… (More)
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2003
2003
Antirheumatic gold compounds have been shown to inhibit NF-kappaB activation by blocking IkappaB kinase (IKK) activity. To… (More)
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1986
1986
In a six-month, randomized, double-blind study at 14 centers, auranofin (3 mg twice daily) was compared with placebo in the… (More)
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1976
1976
Eight patients with rheumatoid arthritis were treated with SK & F D-39162 (auranofin), a new oral gold compound which was… (More)
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