Losartan

Known as: lozartan, Losartan [Chemical/Ingredient], 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol 
The potassium salt form of losartan, a non-peptide angiotensin II antagonist with antihypertensive activity. Losartan potassium selectively and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The Editorialists Reply: Garratt and Bailey suggest that our statement that CABG surgery is the preferred approach to… (More)
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Highly Cited
2006
Highly Cited
2006
Aortic aneurysm and dissection are manifestations of Marfan syndrome (MFS), a disorder caused by mutations in the gene that… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Blood pressure reduction achieved with beta-blockers and diuretics is the best recorded intervention to date for… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The most suitable antihypertensive drug to reduce the risk of cardiovascular disease in patients with hypertension and… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND ACE inhibitors attenuate the detrimental effects of angiotensin II, and improve survival and reduce morbidity in… (More)
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Highly Cited
2001
Highly Cited
2001
A BSTRACT Background Diabetic nephropathy is the leading cause of end-stage renal disease. Interruption of the renin–angiotensin… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Diabetic nephropathy is the leading cause of end-stage renal disease. Interruption of the renin-angiotensin system… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The ELITE study showed an association between the angiotensin II antagonist losartan and an unexpected survival… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Structural and functional alterations of the vasculature may contribute to complications of hypertension. Because… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND To determine whether specific angiotensin II receptor blockade with losartan offers safety and efficacy advantages in… (More)
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