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Nuclear factor-kappaB (NF-kappaB) regulates many genes involved in vascular physiopathology. We have previously observed in vivo… Expand Angiotensin (ANG) II is a powerful and phylogenetically widespread stimulus to thirst and sodium appetite. When it is injected… Expand Angiotensin II stimulates secretion of corticosteroids and ouabain-like activity from adrenocortical cells. Distinct… Expand OBJECTIVE
The aim was to determine angiotensin II receptor binding and its relationship to angiotensin converting enzyme (ACE… Expand Excessive secretion of aldosterone from the adrenal results in the most common form of endocrine hypertension. An understanding… Expand Aspartic acid in the second transmembrane domain is a highly conserved amino acid among the G protein-coupled receptors and is… Expand The present research characterizes a newly discovered ANG II(3-8) (ANG IV) binding site localized in structures associated with… Expand Starting from the recently reported nonpeptidic angiotensin II (AII) receptor antagonists DuP753 (1) and Exp 7711 (2), we have… Expand Both neurons and astrocytes contain specific receptors for angiotensin II (AII). We used selective ligands for the AT1 and AT2… Expand Substantial progress has been made recently in the development of nonpeptide angiotensin II receptor antagonists, a goal that has… Expand