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Linaclotide Acetate

Known as: L-Tyrosine, L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1->6),(2->10),(5->13)-tris(disulfide), Monoacetate (salt) 
The acetate salt form of linaclotide, a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is… 
National Institutes of Health

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linaclotide

Papers overview

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Review
2008
Review
2008
Assays for transfer RNA-dependent amino acid biosynthesis.
2006
2006
Interest heats up in gastrointestinal space
A flurry of investment activity during the first months of 2006 is evidence that some investors are waking up to the untapped… 
2005
2005
Protein S-thiolating activity of plasma membrane gamma-glutamyltransferase: formation of cysteinyl-glicine mixed disulfides on cell protein and in the extracellular microenvironment
2004
2004
Cysteinyl-tRNACys Formation in Methanocaldococcus jannaschii: the Mechanism Is Still Unknown
ABSTRACT Most organisms form Cys-tRNACys, an essential component for protein synthesis, through the action of cysteinyl-tRNA… 
2001
2001
Monoclonal Antibodies FK 1 and WF 6 Define Two Neighboring Ligand Binding Sites on Torpedo Acetylcholine Receptor a-Polypeptide ”
Previous studies have identified the sequence region flanking the invariant vicinal cysteinyl residues at positions 192 and 193… 
Review
1998
Review
1998
Asthma treatment: antileukotriene drugs.
Leukotrienes are derived from the cell membrane phospholipid arachidonic acid and are members of a larger group of molecules… 
1995
1995
Localization of two human autoantigen genes by PCR screening and in situ hybridization--glycyl-tRNA synthetase locates to 7p15 and alanyl-tRNA synthetase locates to 16q22.
Aminoacyl-tRNA synthetases (aminoacyl-RS) catalyze the attachment of an amino acid to its cognate tRNA. Five of 20 human… 
1992
1992
Biosynthese von Peptiden: Ein nichtribosomales System
The biosynthesis of peptides in nonribosomal systems is accomplished by complex multienzymes. These multienzymes assemble the… 
Highly Cited
1976
Highly Cited
1976
Synthesis of delta-(alpha-aminoadipyl)cysteinylvaline and its role in penicillin biosynthesis.
1. The stereoisomers of delta-(alpha-aminoadipyl)-L-cysteinylvaline (LLD, LLL and DLD) were synthesized from valine labelled with… 
1963
1963
Synthesis and biological properties of 1-acetyl-8-lysine-vasopressin.
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