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Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2

Known as: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Leucine Rich Repeat Serine Threonine Protein Kinase 2, Dardarin Protein 
A serine/threonine protein kinase with GTPase activity that contains 12 LEUCINE-rich repeats in its central region and 7 WD repeats C-terminal to its… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (2)

CDC7 protein, humanProtein-Serine-Threonine Kinases
In BloodLRRK2 wt AlleleProcess of secretionantagonists & inhibitors

Narrower (2)

Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2, humanLrrk2 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein Destabilization
Mutations and variations in the leucine-rich repeat kinase 2 (LRRK2) gene are strongly associated with an increased risk to… 
2017
2017
Reduced LRRK 2 in association with retromer dysfunction in post-mortem brain tissue from LRRK 2 mutation carriers
Missense mutations in leucine-rich repeat kinase 2 (LRRK2) are pathogenic for familial Parkinson’s disease. However, it is… 
2016
2016
Detection of TET 2 , KRAS and CBL variants by Next Generation Sequencing and analysis of their correlation with JAK 2 and FLT 3 in childhood AML
Childhood acute myeloid leukemia; Mutation; TET2; KRAS; CBL; Next Generation Sequencing Abstract Background: Acute myeloid… 
2005
2005
Analysis of LRRK 2 G 2019 S and I 2020 T mutations in Parkinson's disease.
Mutations in the leucine-rich repeat kinase 2 (LRRK 2), encoding dardarin protein, have been demonstrated to be linked to… 
Review
2005
Review
2005
Genetics of Parkinson's disease.
The past few years, mutations in 5 genes (a-synuclein, parkin, DJ-1, PINK1, and LRRK2) have been firmly implicated, and… 
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